scholarly journals Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis

Cell Reports ◽  
2019 ◽  
Vol 26 (12) ◽  
pp. 3347-3359.e6 ◽  
Author(s):  
Hao Zhou ◽  
Ziqing Wei ◽  
Shen Wang ◽  
Deqiang Yao ◽  
Rongguang Zhang ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Complex Formation ◽  
Binding Domain ◽  
Snare Complex ◽  
Snare Complex Formation

scholarly journals Synaptotagmin Expands Membrane Fusion Pore by Facilitating SNARE-Complex Formation

2011 ◽  
Vol 100 (3) ◽  
pp. 185a
Author(s):  
Jiajie Diao ◽  
Janghyun Yoo ◽  
Han-Ki Lee ◽  
Yoosoo Yang ◽  
Dae-Hyuk Kweon ◽  
...  
Keyword(s):  
Complex Formation ◽  
Membrane Fusion ◽  
Snare Complex ◽  
Fusion Pore ◽  
Snare Complex Formation

scholarly journals Copper blocks V‐ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion

Traffic ◽  
2019 ◽  
Vol 20 (11) ◽  
pp. 841-850 ◽  
Author(s):  
Gregory E. Miner ◽  
Katherine D. Sullivan ◽  
Chi Zhang ◽  
Logan R. Hurst ◽  
Matthew L. Starr ◽  
...  
Keyword(s):  
Complex Formation ◽  
Atpase Activity ◽  
Snare Complex ◽  
Yeast Vacuole ◽  
Vacuole Fusion ◽  
Snare Complex Formation

scholarly journals Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release

2008 ◽  
Vol 183 (2) ◽  
pp. 323-337 ◽  
Author(s):  
Toshiaki Sakisaka ◽  
Yasunori Yamamoto ◽  
Sumiko Mochida ◽  
Michiko Nakamura ◽  
Kouki Nishikawa ◽  
...  
Keyword(s):  
Complex Formation ◽  
Neurotransmitter Release ◽  
Snare Complex ◽  
Protein Receptor ◽  
Repeat Domain ◽  
Dual Inhibition ◽  
Presynaptic Nerve Terminals ◽  
Synaptic Vesicle Fusion ◽  
Deficient Mice ◽  
Snare Complex Formation

Neurotransmitter release from presynaptic nerve terminals is regulated by soluble NSF attachment protein receptor (SNARE) complex–mediated synaptic vesicle fusion. Tomosyn inhibits SNARE complex formation and neurotransmitter release by sequestering syntaxin-1 through its C-terminal vesicle-associated membrane protein (VAMP)–like domain (VLD). However, in tomosyn-deficient mice, the SNARE complex formation is unexpectedly decreased. In this study, we demonstrate that the N-terminal WD-40 repeat domain of tomosyn catalyzes the oligomerization of the SNARE complex. Microinjection of the tomosyn N-terminal WD-40 repeat domain into neurons prevented stimulated acetylcholine release. Thus, tomosyn inhibits neurotransmitter release by catalyzing oligomerization of the SNARE complex through the N-terminal WD-40 repeat domain in addition to the inhibitory activity of the C-terminal VLD.

Regulation of SNARE complex formation by 8-nitro-cGMP

2010 ◽  
Vol 68 ◽  
pp. e116-e117
Author(s):  
Kouhei Kunieda ◽  
Tomoaki Ida ◽  
Tomohiro Sawa ◽  
Takaaki Akaike ◽  
Makoto Itakura ◽  
...  
Keyword(s):  
Complex Formation ◽  
Snare Complex ◽  
Snare Complex Formation

Author response for "Copper blocks V‐ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion"

2019 ◽  
Author(s):  
Gregory E. Miner ◽  
Katherine D. Sullivan ◽  
Chi Zhang ◽  
Logan R. Hurst ◽  
Matthew L. Starr ◽  
...  
Keyword(s):  
Complex Formation ◽  
Atpase Activity ◽  
Snare Complex ◽  
Author Response ◽  
Yeast Vacuole ◽  
Vacuole Fusion ◽  
Snare Complex Formation

scholarly journals A Stimulation Function of Synaptotagmin-1 in Ternary SNARE Complex Formation Dependent on Munc18 and Munc13

2017 ◽  
Vol 10 ◽  
Author(s):  
Yun Li ◽  
Shen Wang ◽  
Tianzhi Li ◽  
Le Zhu ◽  
Yuanyuan Xu ◽  
...  
Keyword(s):  
Complex Formation ◽  
Snare Complex ◽  
Synaptotagmin 1 ◽  
Snare Complex Formation
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