Viral expression of constitutively active AKT3 induces CST axonal sprouting and regeneration, but also promotes seizures

Experimental Neurology ◽

10.1016/j.expneurol.2021.113961 ◽

2021 ◽

pp. 113961

Author(s):

Thomas J. Campion ◽

Imran S. Sheikh ◽

Rupert D. Smit ◽

Philip H. Iffland ◽

Jie Chen ◽

...

Keyword(s):

Axonal Sprouting ◽

Viral Expression ◽

Constitutively Active

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Constitutively active phosphatidlyinositol 3-kinase (Pl 3-K) and Akt are sufficient to stimulate NHE3: Insights in mechanisms of NHE3 stimulation

Gastroenterology ◽

10.1016/s0016-5085(01)83466-1 ◽

2001 ◽

Vol 120 (5) ◽

pp. A696-A696

Author(s):

W KWON ◽

D JOHNS ◽

M CAVET ◽

J PARK ◽

P TSICHLIS ◽

...

Keyword(s):

Constitutively Active

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Antibodies directed against retained intron 4 of the constitutively active CCK-2 receptor bind to a tumour-specific epitope

Gastroenterology ◽

10.1016/s0016-5085(01)82463-x ◽

2001 ◽

Vol 120 (5) ◽

pp. A496-A496 ◽

Author(s):

P CLARKE ◽

S GRIMES ◽

D MCWILLIAMS ◽

W KLEIE ◽

K KHAN ◽

...

Keyword(s):

Specific Epitope ◽

Retained Intron ◽

Intron 4 ◽

Constitutively Active

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Faculty Opinions recommendation of Expression of a constitutively active mutant of M-Ras in normal bone marrow is sufficient for induction of a malignant mastocytosis/mast cell leukemia, distinct from the histiocytosis/monocytic leukemia induced by expression of activated H-Ras.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1024828.292873 ◽

2005 ◽

Author(s):

Richard L Stevens

Keyword(s):

Bone Marrow ◽

Mast Cell ◽

Normal Bone Marrow ◽

Cell Leukemia ◽

Monocytic Leukemia ◽

Normal Bone ◽

Mast Cell Leukemia ◽

Constitutively Active

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Faculty Opinions recommendation of Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1029764.370951 ◽

2006 ◽

Author(s):

Gerald Spangrude

Keyword(s):

Beta Catenin ◽

Multilineage Differentiation ◽

Differentiation Potential ◽

Constitutively Active ◽

Myeloid Progenitors

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Faculty Opinions recommendation of Constitutively active Akt induces enhanced myelination in the CNS.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1116849.572936 ◽

2008 ◽

Author(s):

Brian Popko

Keyword(s):

Constitutively Active

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Faculty Opinions recommendation of An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.6592956.6728054 ◽

2010 ◽

Author(s):

Charlotte Teunissen

Keyword(s):

Axonal Sprouting ◽

Molecular Control ◽

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Faculty Opinions recommendation of Constitutively active mitogen-activated protein kinase versions reveal functions of Arabidopsis MPK4 in pathogen defense signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717963650.793465461 ◽

2012 ◽

Author(s):

Jörg Kudla

Keyword(s):

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Pathogen Defense ◽

Defense Signaling ◽

Mitogen Activated Protein ◽

Constitutively Active

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Faculty Opinions recommendation of Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717987084.793472326 ◽

2013 ◽

Author(s):

Scott Kopetz

Keyword(s):

Growth Factor ◽

Constitutively Active Mutants ◽

Map Kinase Kinase ◽

Constitutively Active

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The Role of Constitutively Active Prolactin Receptors in the Natural History of Breast Cancer

10.21236/ada470617 ◽

2007 ◽

Author(s):

Kuang-tzu Huang

Keyword(s):

Breast Cancer ◽

Natural History ◽

Prolactin Receptors ◽

Constitutively Active

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The Role of Constitutively Active Prolactin Receptors in the Natural History of Breast Cancer

10.21236/ada504019 ◽

2009 ◽

Author(s):

Kuang-tzu Huang

Keyword(s):

Breast Cancer ◽

Natural History ◽

Prolactin Receptors ◽

Constitutively Active

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