Evaluation of the DuraHeart® Left Ventricular Assist Device for the Treatment of Advanced Heart Failure in Patients Awaiting Heart Transplantation

2013 ◽  
Vol 32 (4) ◽  
pp. S185-S186
Author(s):  
D. Feldman ◽  
Y. Naka ◽  
U. Jorde ◽  
K. Aaronson ◽  
S. Bailey ◽  
...  
2021 ◽  
Vol 15 ◽  
Author(s):  
Michael T Cain ◽  
Michael S Firstenberg ◽  
Joseph C Cleveland

For nearly 60 years, there have been two surgical treatment options for individuals with severe advanced heart failure: heart transplantation or implantation of a left ventricular assist device. As these fields have advanced in parallel, improvements in surgical technique, device development, and patient selection have improved outcomes for both therapies. Development of a comprehensive approach to the management of the most severe forms of advanced heart failure requires a deep understanding of both heart transplantation and durable ventricular assistance, including recent advancements in both fields. This article will review the substantial progress in the fields of heart transplantation and mechanical left ventricular assistance, including recent changes to organ allocation prioritization and left ventricular assist device evaluation, both of which have dramatically influenced practice in these fields.


2016 ◽  
Vol 10 (2) ◽  
pp. 1 ◽  
Author(s):  
Jorge Silva Enciso ◽  
Eric Adler ◽  
Barry Greenberg ◽  
◽  

The heart failure epidemic has led to an increase in the number of patients with advanced heart failure, which is associated with high morbidity and mortality. Current therapies for advanced heart failure are limited to heart transplantation and mechanical circulatory support, with palliative care reserved for those ineligible to receive advanced therapies. Clinical trials of ventricular assist devices for patients with advanced heart failure demonstrate an improvement in survival and quality of life akin to heart transplantation. The Achilles heal of this therapy is the adverse event burden. Patient selection and multidisciplinary care are two of the strategies being used to improve long-term outcomes. Adjunct therapies in combination with left ventricular assist device therapy and advances in device technology in the near future may lessen the number of adverse events. This review summarizes the clinical outcomes, current challenges and future directions of left ventricular assist device therapy.


2015 ◽  
Vol 82 (2) ◽  
Author(s):  
Gianluigi Balestroni ◽  
Giovanna Omarini ◽  
Pierangela Omarini ◽  
Massimo Pistono ◽  
Ugo Corrà ◽  
...  

Background: Advanced heart failure is a challenging disease; the implantable Left Ventricular Assist Device (L-VAD) is becoming a good chance for relieving symptoms and prolong survival in most CHF patients. The emotional impact of L-VAD implantation is thought to be high but, at present, published data are scant about that. Aim of this study was to evaluate the modifications of perceived quality of life (QoL) in a group of patients recently treated with L-VAD implantation, admitted to a residential cardiac rehabilitation program, and to compare the results to those obtained in patients awaiting heart transplantation and recently transplanted. Material and Method: We enrolled 66 patients (pts) with a recent implant of L-VAD, 51 with refractory heart failure awaiting heart transplantation (HT) and 55 recently treated with HT. On day two after admission, all patients underwent a complete psychometric assessment consisting in the compilation of: – Minnesota Living with Heart Failure Questionnaire (MLHFQ) – Beck Anxiety Inventory (BAI) – Beck Depression Inventory-II (BDI - II) Results: L-VAD recipients had significantly higher scores at MLHFQ. Both the total score and the 2 subscales scores (respectively physical and emotional disturbances) were statistically significant when compared with posttransplant patients. Post- transplant pts had the lowest scores regarding anxiety symptoms, while the bearers of device had the highest ones. The same results were obtained for depression scores (BDI - II), both in total score and in the subscales (somatic symptoms and affective symptoms). Conclusions: With an opening scoring, this study showed the development of more relevant psychological troubles in patients treated with L-VAD when compared to those awaiting for heart transplantation and those transplanted.


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