scholarly journals Visually estimated coronary artery calcium score improves SPECT-MPI risk stratification

2021 ◽  
Vol 35 ◽  
pp. 100827
Author(s):  
Cvetan Trpkov ◽  
Alexei Savtchenko ◽  
Zhiying Liang ◽  
Patrick Feng ◽  
Danielle A. Southern ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Risk Stratification ◽  
Coronary Artery Calcium ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Spect Mpi

scholarly journals VISUALLY ESTIMATED CORONARY ARTERY CALCIUM SCORE IMPROVES SPECT-MPI RISK STRATIFICATION

2021 ◽  
Vol 77 (18) ◽  
pp. 1351
Author(s):  
Alexei Savtchenko ◽  
Cvetan Trpkov ◽  
Jane Liang ◽  
Danielle Southern ◽  
Stephen Wilton ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Risk Stratification ◽  
Coronary Artery Calcium ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Spect Mpi

scholarly journals Coronary artery calcium score: current status

2017 ◽  
Vol 50 (3) ◽  
pp. 182-189 ◽  
Author(s):  
Priscilla Ornellas Neves ◽  
Joalbo Andrade ◽  
Henry Monção
Keyword(s):  
Coronary Artery ◽  
Risk Stratification ◽  
Coronary Artery Calcium ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Current Status ◽  
Major Cardiovascular Events ◽  
Asymptomatic Patients

Abstract The coronary artery calcium score plays an Important role In cardiovascular risk stratification, showing a significant association with the medium- or long-term occurrence of major cardiovascular events. Here, we discuss the following: protocols for the acquisition and quantification of the coronary artery calcium score by multidetector computed tomography; the role of the coronary artery calcium score in coronary risk stratification and its comparison with other clinical scores; its indications, interpretation, and prognosis in asymptomatic patients; and its use in patients who are symptomatic or have diabetes.

Coronary Artery Calcium Score and Risk Classification

2016 ◽  
Author(s):  
Christoph I. Lee
Keyword(s):  
Coronary Artery ◽  
Risk Stratification ◽  
Coronary Artery Calcium ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Clinical Context ◽  
Additional Information ◽  
Study Methodology ◽  
Traditional Risk Factors

This chapter, found in the chest pain section of the book, provides a succinct synopsis of a key study examining the use of computed tomography (CT) coronary artery calcium score for cardiovascular risk stratification. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. Researchers report that adding coronary artery calcium score to traditional risk factors produces significant improvements in classification of patients for future risk of coronary heart disease events, especially for intermediate-risk individuals who stand to benefit the most from a risk stratification strategy. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.

scholarly journals Value of coronary artery calcium score in reporting SPECT versus PET myocardial perfusion imaging

2021 ◽  
Vol 22 (Supplement_3) ◽  
Author(s):  
JD Van Dijk ◽  
M Mouden ◽  
JA Van Dalen ◽  
PL Jager
Keyword(s):  
Coronary Artery ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Coronary Artery Calcium ◽  
Event Rate ◽  
Coronary Artery Calcium Score ◽  
Calcium Score ◽  
Spect Mpi ◽  
Event Rates

Abstract Funding Acknowledgements Type of funding sources: None. Background Although it is well known that coronary artery calcium score (CACS) adds value to reporting myocardial perfusion imaging (MPI) SPECT, its added value to reporting PET MPI is not clear. Purpose Hence, our aim was determine the value of adding CACS in the assessment of PET MPI and SPECT MPI and compare the value between both modalities in a low-risk population. Methods We retrospectively included 412 patients, half of them underwent SPECT with CACS and half underwent Rubidium-82 PET with CACS. We created comparable groups using propensity matching, where the PET group was 1:1 matched to a comparable SPECT group, obtained from a large cohort of 4018. Next, we created two types of image sets for the 412 included patients: MPI-only and MPI + CACS. Two experienced physicians interpreted the 824 images as normal, equivocal or abnormal for  ischemia or irreversible defects and were blinded for the used modality. In addition, annualized event rates, defined as the occurrence of all-cause death, non-fatal myocardial infarction or revascularization therapy (PCI or CABG), were compared between the PET and SPECT groups using a follow-up period of 30 months. Results The percentage of scans interpreted as normal was 8% higher with PET-only than with SPECT-only (89 vs 80%, respectively, p = 0.014). Adding CACS to SPECT increased the percentage of scans interpreted as normal from 80% to 86% (p = 0.014), whereas this effect was absent for PET (p = 0.77). Adding CACS reduced the frequency of equivocal scans from 12% and 6% to 0% for both SPECT and PET, respectively. Furthermore, adding CACS resulted in 5% more abnormal interpreted scans for both PET (4.9 to 10%, p = 0.003) and SPECT (8.7 to 14%, p = 0.04). The annualized event rate was 2.7% for the SPECT and 3.5% for the PET group (p = 0.58). The annualized event rates for images interpreted as normal were comparable between all four types of image sets and varied between 0.7-2.0% (p > 0.084). The annualized event rate for equivocal and abnormal scans was higher for PET-only (23%) compared to SPECT-only (4.8%, p < 0.001). Moreover, the event rate for equivocal and abnormal SPECT + CACS  (8.6%) was also higher than for SPECT-only (4.8%, p = 0.04), whereas this difference was absent for PET (p = 0.07). Conclusion Adding CACS increases the percentage of scans interpreted as normal for SPECT MPI while the event rate remained unchanged. Adding CACS to PET did not influence the percentage of scans interpreted as normal, limiting the effect of adding CACS to PET in a low-risk population.

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