Quantification of Organ Volume Changes and Impact of Interfraction Motion on Planning Contours Using Deformable Image Registration for Head and Neck Radiation Therapy

2015 ◽  
Vol 93 (3) ◽  
pp. E608-E609
Author(s):  
J. Kim ◽  
C. Liu ◽  
A.D. Kumarasiri ◽  
M. Chetvertkov ◽  
J.J. Gordon ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Image Registration ◽  
Head And Neck ◽  
Deformable Image Registration ◽  
Volume Changes ◽  
Organ Volume ◽  
Head And Neck Radiation ◽  
Interfraction Motion

scholarly journals Evaluation of Deformable Image Registration Methods for Dose Monitoring in Head and Neck Radiotherapy

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Bastien Rigaud ◽  
Antoine Simon ◽  
Joël Castelli ◽  
Maxime Gobeli ◽  
Juan-David Ospina Arango ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Image Registration ◽  
Head And Neck ◽  
Intensity Modulated Radiation Therapy ◽  
Deformable Image Registration ◽  
Free Form ◽  
Registration Accuracy ◽  
Dose Accumulation ◽  
Dose Monitoring ◽  
Dose Accuracy

In the context of head and neck cancer (HNC) adaptive radiation therapy (ART), the two purposes of the study were to compare the performance of multiple deformable image registration (DIR) methods and to quantify their impact for dose accumulation, in healthy structures. Fifteen HNC patients had a planning computed tomography (CT0) and weekly CTs during the 7 weeks of intensity-modulated radiation therapy (IMRT). Ten DIR approaches using different registration methods (demons or B-spline free form deformation (FFD)), preprocessing, and similarity metrics were tested. Two observers identified 14 landmarks (LM) on each CT-scan to compute LM registration error. The cumulated doses estimated by each method were compared. The two most effective DIR methods were the demons and the FFD, with both the mutual information (MI) metric and the filtered CTs. The corresponding LM registration accuracy (precision) was 2.44 mm (1.30 mm) and 2.54 mm (1.33 mm), respectively. The corresponding LM estimated cumulated dose accuracy (dose precision) was 0.85 Gy (0.93 Gy) and 0.88 Gy (0.95 Gy), respectively. The mean uncertainty (difference between maximal and minimal dose considering all the 10 methods) to estimate the cumulated mean dose to the parotid gland (PG) was 4.03 Gy (SD = 2.27 Gy, range: 1.06–8.91 Gy).

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