Influence of skin permeation enhancers on the transdermal delivery of palonosetron: An in vitro evaluation

2018 ◽  
Vol 16 (3) ◽  
pp. 192-197 ◽  
Author(s):  
Anroop B. Nair ◽  
Shery Jacob ◽  
Bandar E. Al-Dhubiab ◽  
Rakan Naser Alhumam
Keyword(s):  
Transdermal Delivery ◽  
Skin Permeation ◽  
Permeation Enhancers ◽  
In Vitro Evaluation

Transdermal Delivery of Metoprolol II: In-Vitro Skin Permeation and Bioavailability in Hairless Rats

1995 ◽  
Vol 84 (2) ◽  
pp. 158-160 ◽  
Author(s):  
Tapash K. Ghosh ◽  
Joseph Adir ◽  
Si‐Ling Xiang ◽  
Samuel Onyilofur
Keyword(s):  
Transdermal Delivery ◽  
Skin Permeation ◽  
In Vitro Skin Permeation

Skin permeation of retinol in Tween 20-based deformable liposomes: in-vitro evaluation in human skin and keratinocyte models

2006 ◽  
Vol 58 (2) ◽  
pp. 161-166 ◽  
Author(s):  
Yu-Kyoung Oh ◽  
Mi Young Kim ◽  
Jee-Young Shin ◽  
Tae Woon Kim ◽  
Mi-Ok Yun ◽  
...  
Keyword(s):  
Human Skin ◽  
Skin Permeation ◽  
Tween 20 ◽  
In Vitro Evaluation

Transdermal Delivery of Targeted Nanoparticles and in vitro Evaluation

2021 ◽  
pp. 411-443
Author(s):  
Ceyda Ekentok Atıcı ◽  
Aysun Çelik Soysal ◽  
Ali Demir Sezer
Keyword(s):  
Transdermal Delivery ◽  
In Vitro Evaluation ◽  
Targeted Nanoparticles

Preparation and the in Vitro Evaluation of Nanoemulsion System for the Transdermal Delivery of Granisetron Hydrochloride

2010 ◽  
Vol 58 (8) ◽  
pp. 1015-1019 ◽  
Author(s):  
Wen-wu Zheng ◽  
Ling Zhao ◽  
Yu-meng Wei ◽  
Yun Ye ◽  
Shun-han Xiao
Keyword(s):  
Transdermal Delivery ◽  
In Vitro Evaluation

scholarly journals Design, development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxib

2007 ◽  
Vol 57 (3) ◽  
pp. 315-332 ◽  
Author(s):  
Sanjula Baboota ◽  
Faiyaz Shakeel ◽  
Alka Ahuja ◽  
Javed Ali ◽  
Sheikh Shafiq
Keyword(s):  
Transdermal Delivery ◽  
Permeability Coefficient ◽  
Skin Permeation ◽  
Tween 80 ◽  
Surfactant Mixture ◽  
Design Development ◽  
Paw Edema ◽  
Steady State Flux ◽  
Nanoemulsion Gel

Design, development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxibThe aim of the present study was to investigate the potential of nanoemulsion formulations for transdermal delivery of celecoxib (CXB). Thein vitroskin permeation profile of optimized formulations was compared with CXB gel and nanoemulsion gel. Significant increase in the steady state flux (Jss), permeability coefficient (Kp) and enhancement ratio (Er) was observed in nanoemulsion formulations T1 and T2 (p< 0.05). The highest value of these permeability parameters was obtained in formulation T2, which consisted of 2% (m/m) of CXB, 10% (m/m) of oil phase (Sefsol 218 and Triacetin), 50% (m/m) of surfactant mixture (Tween-80 and Transcutol-P) and 40% (m/m) water. The anti-inflammatory effects of formulation T2 showed a significant increase (p< 0.05) in inhibition after 24 h compared to CXB gel and nanoemulsion gel on carrageenan-induced paw edema in rats. These results suggested that nanoemulsions are potential vehicles for improved transdermal delivery of CXB.

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