scholarly journals Prompt Reversal of Airway Obstruction Secondary to Angiotensin Converting Enzyme Inhibitor (ACEI) Induced Angioedema by Ecallantide: A Case Report

2012 ◽  
Vol 129 (2) ◽  
pp. AB220 ◽  
Author(s):  
J.R. Cohn ◽  
C. McDaniel ◽  
N. Richards ◽  
C. Au ◽  
M. Baram
2016 ◽  
Vol 23 (3) ◽  
pp. 166-169 ◽  
Author(s):  
Beatriz Frutuoso ◽  
Joana Esteves ◽  
Mafalda Silva ◽  
Pedro Gil ◽  
Ana Cristina Carneiro ◽  
...  

2019 ◽  
Vol 69 (5) ◽  
pp. 521-526
Author(s):  
Flora Margarida Barra Bisinotto ◽  
Beatrice Cavalcanti Seabra ◽  
Fernando B. Prata Lóes ◽  
Laura Bisinotto Martins ◽  
Luciano Alves Matias da Silveira

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Neil H. Crooks ◽  
Jaimin Patel ◽  
Lavanya Diwakar ◽  
Fang Gao Smith

We describe the case of a 75-year-old woman who presented with massive tongue and lip swelling secondary to angiotensin-converting enzyme inhibitor-induced angioedema. An awake fibre-optic intubation was performed because of impending airway obstruction. As there was no improvement in symptoms after 72 hours, the selective bradykinin B2 receptor antagonist icatibant (Firazyr) was administered and the patient’s trachea was successfully extubated 36 hours later. To our knowledge this is the first documented case of icatibant being used for the treatment of angiotensin-converting enzyme inhibitor-induced angioedema in the United Kingdom and represents a novel therapeutic option in its management.


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