scholarly journals Drug-induced subacute cutaneous lupus erythematosus in previously diagnosed systemic lupus erythematosus patients - a case series

2021 ◽  
Author(s):  
Emily Keyes ◽  
Madison Grinnell ◽  
Thomas Vazquez ◽  
DeAnna Diaz ◽  
Preethi Thomas ◽  
...  
2018 ◽  
Vol 2 (1) ◽  
pp. 59-63
Author(s):  
Alyx Rosen ◽  
Evan Darwin ◽  
Jennifer N Choi

Capecitabine is a fluoropyrimidine chemotherapy prodrug of 5-fluorouracil (5-FU) used in the treatment of metastatic breast and colorectal cancers. Drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) is a rare side effect of capecitabine therapy, with eight cases previously reported. We report a case of DI-SCLE in a patient with a documented history of systemic lupus erythematosus (SLE). This is the second documented case of DI-SCLE in a patient with a past medical history of SLE, and provides evidence that there may be an increased risk of DI-SCLE in these patients. Further research should examine whether patients with SLE are at greater risk for this adverse event. 


2003 ◽  
Vol 40 (140) ◽  
pp. 209-211
Author(s):  
H Sripathi ◽  
M Dahal ◽  
A Basu

Sub acute Cutaneous Lupus Erythematosus (SCLE) is a distinct subset of LupusErythematosus. It can present as non scarring psoriasiform or annular polycycliclesions. About half the patients fulfil the criteria of the American RheumatismAssociation for systemic lupus erythematosus. In this report, we present the case of a45 years old male who came with psoriasiform depigmented plaques and papulo-vesicular lesions developed after taking some medication. Clinically diagnosed as subacute cutaneous lupus erythematosus with acral vitiligo. A histopathological studyand urine analysis however revealed presence of pseudo porphyria along with theSCLE. Although SCLE is not a rare disease, the association of it with pseudo porphyriaand vitiligo is of significance as the treatment for SCLE and pseudo porphyria isphoto protection and for the vitiligo it is photo chemotherapy.ABSTRACTKey Words: Sub acute cutaneous lupus erythematosus, pseudo porphyria,vitiligo, psoriasiform eruptions.


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