Structural Basis for Resistance of the Genotype 2b Hepatitis C Virus NS5B Polymerase to Site A Non-Nucleoside Inhibitors

2009 ◽  
Vol 390 (5) ◽  
pp. 1048-1059 ◽  
Author(s):  
Edwin H. Rydberg ◽  
Antonella Cellucci ◽  
Linda Bartholomew ◽  
Marco Mattu ◽  
Gaetano Barbato ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Structural Basis ◽  
Nucleoside Inhibitors ◽  
Ns5b Polymerase

Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review

2016 ◽  
Vol 17 (13) ◽  
pp. 1560-1576 ◽  
Author(s):  
Yuanchao Xie ◽  
Comfort Alicha Ogah ◽  
Xiangrui Jiang ◽  
Jianfeng Li ◽  
Jingshan Shen
Keyword(s):  
Systematic Review ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Nucleoside Inhibitors ◽  
Ns5b Polymerase

scholarly journals Binding Site Characterization and Resistance to a Class of Non-nucleoside Inhibitors of the Hepatitis C Virus NS5B Polymerase

2005 ◽  
Vol 280 (47) ◽  
pp. 39260-39267 ◽  
Author(s):  
George Kukolj ◽  
Graham A. McGibbon ◽  
Ginette McKercher ◽  
Martin Marquis ◽  
Sylvain Lefèbvre ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Binding Site ◽  
Site Characterization ◽  
Nucleoside Inhibitors ◽  
Ns5b Polymerase

Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives

2004 ◽  
Vol 14 (1) ◽  
pp. 119-124 ◽  
Author(s):  
Pierre L Beaulieu ◽  
Michael Bös ◽  
Yves Bousquet ◽  
Gulrez Fazal ◽  
Jean Gauthier ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Benzimidazole Derivatives ◽  
Nucleoside Inhibitors ◽  
Ns5b Polymerase

Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition

2006 ◽  
Vol 361 (1) ◽  
pp. 33-45 ◽  
Author(s):  
Bichitra K. Biswal ◽  
Meitian Wang ◽  
Maia M. Cherney ◽  
Laval Chan ◽  
Constantin G. Yannopoulos ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Mechanism Of Inhibition ◽  
Nucleoside Inhibitors ◽  
Ns5b Polymerase

The discovery and structure–activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase

2010 ◽  
Vol 20 (9) ◽  
pp. 2968-2973 ◽  
Author(s):  
Matthew G. LaPorte ◽  
Tandy L. Draper ◽  
Lori E. Miller ◽  
Charles W. Blackledge ◽  
Lara K. Leister ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Ns5b Polymerase
Sign in / Sign up

Export Citation Format

Share Document