scholarly journals Posterior urethral valves: Risk factors for progression to renal failure

2016 ◽  
Vol 12 (3) ◽  
pp. 179.e1-179.e7 ◽  
Author(s):  
Aylin N. Bilgutay ◽  
David R. Roth ◽  
Edmond T. Gonzales ◽  
Nicolette Janzen ◽  
Wei Zhang ◽  
...  
2015 ◽  
Vol 37 (4) ◽  
pp. 267-273 ◽  
Author(s):  
José María Martínez ◽  
Narcis Masoller ◽  
Roland Devlieger ◽  
Esther Passchyn ◽  
Olga Gómez ◽  
...  

Objective: To report the results of fetal cystoscopic laser ablation of posterior urethral valves (PUV) in a consecutive series in two referral centers. Methods: Twenty pregnant women with a presumptive isolated PUV were treated with fetal cystoscopy under local anesthesia. Identification and fulguration of the PUV by one or several firing-contacts with diode laser were attempted. Perinatal and long-term outcomes were prospectively recorded. Results: The median gestational age at procedure was 18.1 weeks (range 15.0-25.6), and median operation time was 24 min (range 15-40). Access to the urethra was achieved in 19/20 (95%) cases, and postoperative, normalization of bladder size and amniotic fluid was observed in 16/20 (80%). Overall, there were 9 (45%) terminations of pregnancy and 11 women (55%) delivered a liveborn baby at a mean gestational age of 37.3 (29.1-40.2) weeks. No infants developed pulmonary hypoplasia and all were alive at 15-110 months. Eight (40% of all fetuses, 72.7% of newborns) had normal renal function and 3 (27.3%) had renal failure awaiting renal transplantation. Conclusion: Fetoscopic laser ablation for PUV can achieve bladder decompression and amniotic fluid normalization with a single procedure in selected cases with anyhydramnios. There is still a significant risk of progression to renal failure pre or postnatally.


2008 ◽  
Vol 180 (4S) ◽  
pp. 1705-1708 ◽  
Author(s):  
William DeFoor ◽  
Curtis Clark ◽  
Elizabeth Jackson ◽  
Pramod Reddy ◽  
Eugene Minevich ◽  
...  

Author(s):  
Termos S ◽  
Alkabbani M ◽  
Alali M ◽  
AlSaleh A ◽  
Sanjad S ◽  
...  

Author(s):  
Grenville Fox ◽  
Nicholas Hoque ◽  
Timothy Watts

This chapter provides background information on fetal and neonatal renal development, physiology, and function. Detailed information is given on management of common, antenatally diagnosed, renal anomalies (renal pelvis dilatation/hydronephrosis); post-natal diagnoses (hypospadius, hydrocele); posterior urethral valves; polycystic kidney disease; and rarer diagnoses. There is a guideline on the management of acute renal failure in the newborn, and information on dialysis.


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