scholarly journals A combined fractional flow reserve and optical coherence tomography approach to guide coronary artery bypass grafting: A pilot study

2018 ◽  
Vol 156 (3) ◽  
pp. 997-1000 ◽  
Author(s):  
Francesco Fracassi ◽  
Tomoyo Sugiyama ◽  
Erika Yamamoto ◽  
Brian Ghoshhajra ◽  
Amy Gin ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Pilot Study ◽  
Coronary Artery Bypass ◽  
Fractional Flow Reserve ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Fractional Flow ◽  
Flow Reserve

scholarly journals Fractional Flow Reserve Versus Angiographically-Guided Coronary Artery Bypass Grafting

2018 ◽  
Vol 72 (22) ◽  
pp. 2732-2743 ◽  
Author(s):  
Anne Langhoff Thuesen ◽  
Lars Peter Riber ◽  
Karsten Tange Veien ◽  
Evald Høj Christiansen ◽  
Svend Eggert Jensen ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Fractional Flow Reserve ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Fractional Flow ◽  
Artery Bypass Grafting ◽  
Flow Reserve

Health-Related Quality of Life and Angina in Fractional Flow Reserve- Versus Angiography-Guided Coronary Artery Bypass Grafting: From the Randomized Fractional Flow Reserve- Versus Angiography-Guided Coronary Artery Bypass Grafting

2021 ◽  
Author(s):  
Anne Langhoff Thuesen ◽  
Lars Peter Riber ◽  
Karsten Tange Veien ◽  
Evald Høj Christiansen ◽  
Svend Eggert Jensen ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Fractional Flow Reserve ◽  
Graft Failure ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Fractional Flow ◽  
Artery Bypass Grafting ◽  
Flow Reserve

Background: In coronary artery bypass grafting (CABG), the use of fractional flow reserve (FFR) is insufficiently investigated. Stenosis assessment usually relies on visual estimates of lesion severity. This study evaluated health-related quality of life (HRQoL) and angina after FFR- versus angiography-guided CABG. Methods: One hundred patients referred for CABG were randomized to FFR- or angiography-guided CABG. In the FFR group, lesions with FFR>0.80 were deferred, while the surgeon was blinded to the FFR values in the angiography group. Before and 6 months after CABG, HRQoL was assessed by the health state classifier EQ-5D of the EuroQoL 5-level instrument and angina status based on the Canadian Cardiovascular Society classification system were registered. Results: Six-month angiography included FFR evaluations of deferred lesions. In total, completed EQ-5D of the EuroQoL 5-level instrument questionnaires were available in 86 patients (43 in the FFR versus 43 in the angiography-guided group). HRQoL was significantly improved and angina significantly decreased from baseline to 6 months after CABG with no difference between the randomization groups. Graft failure rates and clinical outcomes were similar in both groups. Patients with graft failure or FFR<0.80 of the previous deferred lesions had significantly lower visual analogue scale scores (78.7±14.2 versus 86.8±14.7, P =0.004) and more angina compared with patients without graft failure or FFR≥0.80 at 6-month follow-up. Conclusions: FFR- versus angiography-guided CABG demonstrated similar improvements in HRQoL and angina 6 months after CABG. Graft failure or low FFR in deferred lesions were associated with low HRQoL and angina. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02477371

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