Current State of Nerve Stimulation Technique for Lower Urinary Tract Dysfunction in Children

2011 ◽  
Vol 185 (5) ◽  
pp. 1571-1577 ◽  
Author(s):  
Mario De Gennaro ◽  
Maria Luisa Capitanucci ◽  
Giovanni Mosiello ◽  
Antonio Zaccara
BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shan Chen ◽  
Siyou Wang ◽  
Yunqiu Gao ◽  
Xiaolian Lu ◽  
Jiasheng Yan ◽  
...  

Abstract Background Sacral neuromodulation (SNM) has become an effective therapy for patients with lower urinary tract dysfunction (LUTD) who do not respond to conservative treatment. However, an effective treatment strategy for patients who fail SNM has not yet been identified. An option for LUTD is needed when the clinical response to the SNM diminishes. Case presentation A 51-year-old Chinese man presented to an outpatient clinic complaining of difficulty in urination for > 3 years. The patient also complained of urinary frequency and urgency, accompanied by perineal discomfort. He was diagnosed with LUTD based on his symptoms and previous examinations. The patient underwent sacral neuromodulation with a permanent implantable pulse generator (IPG) (provided free of charge by Chengnuo Medical Technology Co., Ltd.; General Stim, Hangzhou, China) in the left buttock, as he participated in the company’s clinical trial to test the long-term effects of IPG. He reported loss of efficacy of the device 3 months after the implantation. We performed bilateral electrical pudendal nerve stimulation (EPNS) therapy for him. After 2 weeks of treatment, he began to report smooth voiding within 2 h after EPNS, and a moderate improvement in urinary frequency, urgency, and perineal discomfort. After 4 weeks of EPNS, the patient reported > 50% improvement in his urination, evaluated with the short form of the International Consultation on Incontinence Questionnaire for Male Lower Urinary Tract Symptoms. He reported smooth voiding, moderate improvements in urinary frequency and urgency, and the disappearance of the perineal discomfort. He also reported improved sleep and erections. The patient was discharged after 8 weeks of EPNS treatment. Conclusion EPNS could be an option as an additional therapy for patients with LUTD who have failed SNM.


2009 ◽  
Vol 182 (4S) ◽  
pp. 2056-2061 ◽  
Author(s):  
Maria Luisa Capitanucci ◽  
Daniela Camanni ◽  
Francesca Demelas ◽  
Giovanni Mosiello ◽  
Antonio Zaccara ◽  
...  

2015 ◽  
Vol 68 (5) ◽  
pp. 859-867 ◽  
Author(s):  
Marc P. Schneider ◽  
Tobias Gross ◽  
Lucas M. Bachmann ◽  
Bertil F.M. Blok ◽  
David Castro-Diaz ◽  
...  

2001 ◽  
Vol 166 (3) ◽  
pp. 914-918 ◽  
Author(s):  
MICHAEL R. van BALKEN ◽  
VERA VANDONINCK ◽  
KAREL W.H. GISOLF ◽  
HENK VERGUNST ◽  
LAMBERTUS A.L.M. KIEMENEY ◽  
...  

2003 ◽  
Vol 6 (6) ◽  
pp. 702
Author(s):  
F Cappellano ◽  
P Bertapelle ◽  
L Spreafico ◽  
G del Popolo ◽  
E Kocjancic ◽  
...  

2007 ◽  
Vol 7 ◽  
pp. 1036-1045 ◽  
Author(s):  
Zahid Hussain ◽  
Simon C. W. Harrison

The aim of this review is to provide an update on the use of neuromodulation using sacral nerve stimulation for the treatment of disorders of the lower urinary tract. Neuromodulation using the InterStim® system (Medtronic Inc.) is now accepted as an established therapeutic option for patients with detrusor overactivity, and for women with retention or severe voiding difficulties. However, the use of nerve stimulation in modulating lower urinary tract function has to be regarded as a technique that is in its infancy. Much has yet to be learned about the mechanism by which neuromodulation exerts its effects and there is a need to better define the clinical indications for the treatment. There is also work to be done in terms of optimising stimulation delivery, both in anatomical and electronic terms.


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