scholarly journals A workflow for patient-specific fluid–structure interaction analysis of the mitral valve: A proof of concept on a mitral regurgitation case

2019 ◽  
Vol 74 ◽  
pp. 153-161 ◽  
Author(s):  
Benedetta Biffi ◽  
Maurizio Gritti ◽  
Agata Grasso ◽  
Elena G. Milano ◽  
Marianna Fontana ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Interaction Analysis ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Proof Of Concept ◽  
Fluid Structure ◽  
Structure Interaction

scholarly journals Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer

Prosthesis ◽  
2020 ◽  
Vol 2 (2) ◽  
pp. 65-75 ◽  
Author(s):  
Milan Toma ◽  
Daniel R. Einstein ◽  
Charles H. Bloodworth ◽  
Keshav Kohli ◽  
Richard P. Cochran ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Interaction Analysis ◽  
Fluid Structure Interaction ◽  
Mitral Valve Regurgitation ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Mitral Regurgitation Severity ◽  
Subject Specific ◽  
Valve Model

Mitral regurgitation imposes a significant symptomatic burden on patients who are not candidates for conventional surgery. For these patients, transcatheter repair and replacement devices are emerging as alternative options. One such device is an intravalvular balloon or spacer that is inserted between the mitral valve leaflets to fill the gap that gives rise to mitral regurgitation. In this study, we apply a large-deformation fluid-structure interaction analysis to a fully 3D subject-specific mitral valve model to assess the efficacy of the intra-valvular spacer for reducing mitral regurgitation severity. The model includes a topologically 3D subvalvular apparatus with unprecedented detail. Results show that device fixation and anchoring at the location of the subject’s regurgitant orifice is imperative for optimal reduction of mitral regurgitation.

scholarly journals Fluid–Structure Interaction Analysis of Papillary Muscle Forces Using a Comprehensive Mitral Valve Model with 3D Chordal Structure

2015 ◽  
Vol 44 (4) ◽  
pp. 942-953 ◽  
Author(s):  
Milan Toma ◽  
Morten Ø. Jensen ◽  
Daniel R. Einstein ◽  
Ajit P. Yoganathan ◽  
Richard P. Cochran ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Papillary Muscle ◽  
Interaction Analysis ◽  
Fluid Structure Interaction ◽  
Muscle Forces ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Valve Model
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