Background and Objective:
Carpal tunnel syndrome (CTS) is the most common form of nerve entrapment. Clinically, various signs and symptoms compare due to overexposure to mechanical vibrations transmitted to the wrist bones and
cartilage, resulting in compression of the sensory and motor nerve fibers of median nerve. Early symptoms include nocturnal paresthesia and electromyography reveals reduced sensory nerve conduction velocity. Aim of this study was to evaluate
the efficacy of a dietary integrator composed of acetyl-L-carnitine, α-lipoic acid,quercetin, bromelain, pantothenic acid, C
and B1 and B2 and B6 and B12 vitamins in patients with early (minimal) carpal tunnel syndrome.
Methods:
36 patients (28 female and 8 male) with early CTS characterized by sensory nerve demyelination and inflammation of the transverse carpal ligament. Patients were divided into two groups, group A (18 patients received physical therapy) and group B (18 patients, received physical therapy and an oral integrator). Clinical (sleep quality questionnaire to
measure severity of paresthesia) and neurophysiological assessment (Sensory Nerve Conduction Velocity) performed at
baseline, and then at 30 and 60 days after treatment.
Results:
Sleep quality and Sensory Nerve Conduction Velocity data analysis show improvement in both groups at 30 and 60
days, with statistically difference between them in both time of analysis.
Conclusions:
In the early CTS, with sensory fibers damage, use of dietary integrator, such as Micronil Dol®, composed
composed of acetyl-L-carnitine, α-lipoic acid,quercetin, bromelain, pantothenic acid, C and B1 and B2 and B6 and B12 vitamins can be effective in quick recovery of median nerve sensory.
A conduction velocity adapted eikonal model for electrophysiology problems with re-excitability evaluation
