Early saphenous vein graft disease following coronary artery bypass grafting

2018 ◽  
Vol 36 (2) ◽  
pp. 83-85 ◽  
Author(s):  
Philemon Gukop ◽  
Aziz Momin
2018 ◽  
Vol 46 (12) ◽  
pp. 4907-4919 ◽  
Author(s):  
Jing Gao ◽  
Yin Liu ◽  
Yu-Ming Li

Saphenous vein graft disease (SVGD) is a type of vascular disease that may develop after coronary artery bypass grafting (CABG). SVGD seriously affects the short-term and long-term effects of CABG and increases the incidence of major adverse cardiovascular events. It is very important to identify patients at greatest risk and carry out prevention and treatment measures to determine the risk factors for SVGD. Many factors contribute to SVGD when the vein is grafted into an arterial environment, such as surgery-related factors, smoking, diabetes mellitus, hyperlipidemia, and others. In this review, we discuss the risk factors for SVGD, current surgical and pharmacologic therapies with which to manage SVGD, and the prevention of SVGD.


2014 ◽  
Vol 37 (5) ◽  
pp. 338 ◽  
Author(s):  
Bora Demircelik ◽  
Muzaffer Cakmak ◽  
Yunus Nazli ◽  
Ozgul M Gurel ◽  
Nermin Akkaya ◽  
...  

Purpose: Saphenous vein graft disease (SVGD), defined as an occlusion of 50% or more of the SVG excluding distal anastomotic occlusion, is an important predictor of morbidity after coronary artery bypass grafting (CABG). Late graft occlusion is a serious complication that often limits the use of the saphenous vein as a coronary bypass graft. Late graft occlusion is particularly common in old, degenerated venous grafts with advanced atherosclerotic plaques. Adropin has been implicated in the homeostatic control of metabolism. The purpose of this study was to investigate whether serum adropin levels are associated with late SVGD following CABG. Methods: Thirty-eight patients with SVGD involving at least one graft (occluded group; 14 females, 24 males) and 42 patients with a patent saphenous vein graft (patent group; 15 females, 27 males) were enrolled in this study. Venous blood samples were taken from all of the participants to measure plasma adropin levels using an enzyme-linked immunsorbent assay kit. Results: The mean adropin level was significantly lower in the occluded group than in the patent group (3.2 ± 0.71 vs. 4.9 ± 1.51 ng/mL, p < 0.001). Multivariate regression analysis showed that the adropin level was the independent predictor of late saphenous vein graft occlusion. Conclusions: Adropin levels are lower in patients with late saphenous vein graft occlusion and these reduced adropin levels, together with other factors, may lead to saphenous vein graft occlusion. Larger and prospective studies are needed to determine if adropin plays a role in the pathogenesis of SVGD.


2005 ◽  
Vol 129 (6) ◽  
pp. 1432-1433 ◽  
Author(s):  
Yoshiharu Nishimura ◽  
Yoshitaka Okamura ◽  
Takeshi Hiramatsu ◽  
Hideaki Mori ◽  
Hiroki Hayashi ◽  
...  

2001 ◽  
Vol 42 (5) ◽  
pp. 553-562 ◽  
Author(s):  
Yoshitaka Iwama ◽  
Hiroshi Mokuno ◽  
Yoshiro Watanabe ◽  
Kazunori Shimada ◽  
Hisashi Yokoi ◽  
...  

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