scholarly journals Relationship between Plasma Homocysteine Levels and Saphenous Vein Graft Disease after Coronary Artery Bypass Grafts.

2001 ◽  
Vol 42 (5) ◽  
pp. 553-562 ◽  
Author(s):  
Yoshitaka Iwama ◽  
Hiroshi Mokuno ◽  
Yoshiro Watanabe ◽  
Kazunori Shimada ◽  
Hisashi Yokoi ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Saphenous Vein ◽  
Saphenous Vein Graft ◽  
Artery Bypass ◽  
Plasma Homocysteine ◽  
Coronary Artery Bypass Grafts ◽  
Bypass Grafts ◽  
Vein Graft Disease ◽  
Graft Disease ◽  
Saphenous Vein Graft Disease

scholarly journals Review of risk factors, treatment, and prevention of saphenous vein graft disease after coronary artery bypass grafting

2018 ◽  
Vol 46 (12) ◽  
pp. 4907-4919 ◽  
Author(s):  
Jing Gao ◽  
Yin Liu ◽  
Yu-Ming Li
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Saphenous Vein ◽  
Saphenous Vein Graft ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Vein Graft Disease ◽  
Graft Disease ◽  
Saphenous Vein Graft Disease

Saphenous vein graft disease (SVGD) is a type of vascular disease that may develop after coronary artery bypass grafting (CABG). SVGD seriously affects the short-term and long-term effects of CABG and increases the incidence of major adverse cardiovascular events. It is very important to identify patients at greatest risk and carry out prevention and treatment measures to determine the risk factors for SVGD. Many factors contribute to SVGD when the vein is grafted into an arterial environment, such as surgery-related factors, smoking, diabetes mellitus, hyperlipidemia, and others. In this review, we discuss the risk factors for SVGD, current surgical and pharmacologic therapies with which to manage SVGD, and the prevention of SVGD.

scholarly journals Adropin: A New Marker for Predicting Late Saphenous Vein Graft Disease after Coronary Artery Bypass Grafting

2014 ◽  
Vol 37 (5) ◽  
pp. 338 ◽  
Author(s):  
Bora Demircelik ◽  
Muzaffer Cakmak ◽  
Yunus Nazli ◽  
Ozgul M Gurel ◽  
Nermin Akkaya ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Saphenous Vein ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Graft Occlusion ◽  
Vein Graft Disease ◽  
Graft Disease ◽  
Saphenous Vein Graft Disease

Purpose: Saphenous vein graft disease (SVGD), defined as an occlusion of 50% or more of the SVG excluding distal anastomotic occlusion, is an important predictor of morbidity after coronary artery bypass grafting (CABG). Late graft occlusion is a serious complication that often limits the use of the saphenous vein as a coronary bypass graft. Late graft occlusion is particularly common in old, degenerated venous grafts with advanced atherosclerotic plaques. Adropin has been implicated in the homeostatic control of metabolism. The purpose of this study was to investigate whether serum adropin levels are associated with late SVGD following CABG. Methods: Thirty-eight patients with SVGD involving at least one graft (occluded group; 14 females, 24 males) and 42 patients with a patent saphenous vein graft (patent group; 15 females, 27 males) were enrolled in this study. Venous blood samples were taken from all of the participants to measure plasma adropin levels using an enzyme-linked immunsorbent assay kit. Results: The mean adropin level was significantly lower in the occluded group than in the patent group (3.2 ± 0.71 vs. 4.9 ± 1.51 ng/mL, p < 0.001). Multivariate regression analysis showed that the adropin level was the independent predictor of late saphenous vein graft occlusion. Conclusions: Adropin levels are lower in patients with late saphenous vein graft occlusion and these reduced adropin levels, together with other factors, may lead to saphenous vein graft occlusion. Larger and prospective studies are needed to determine if adropin plays a role in the pathogenesis of SVGD.

scholarly journals The roles of CHA2DS2-VASc score and blood inflammatory parameters in predicting the patency of saphenous vein grafts in patients with coronary artery bypass graft surgery

2021 ◽  
Vol 8 (10) ◽  
pp. 601-607
Author(s):  
Cihan Aydın ◽  
Mustafa Abanoz
Keyword(s):  
Coronary Artery ◽  
Saphenous Vein ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
Bypass Graft ◽  
Vein Graft Disease ◽  
Group 2 ◽  
Graft Disease ◽  
Saphenous Vein Graft Disease ◽  
Group 1

Objective: Coronary artery bypass graft (CABG) surgery is a common treatment method in which saphenous vein grafts (SVG) and arterial grafts are used together in severe coronary artery disease. The CHA2DS2-VASc score is used to predict thromboembolic events in nonvalvular atrial fibrillation as well as to predict prognosis in cardiovascular events.  In this study, we planned to research the relation between CHA2DS2-VASc score and postoperative SVG patency rates in patients undergoing CABG. Materials and Methods: One hundred seventeen patients with angina after CABG surgery who underwent coronary angiography were analyzed retrospectively. Stenosis of 50% or more in at least one saphenous vein graft was accepted as saphenous vein graft disease (SVGD). We compared these patients in two groups concerning the presence of 50% or more stenosis in the SVG. These two groups were; Group 1 (n = 66); with saphenous vein graft disease, Group 2 (n = 51) without saphenous vein graft disease, respectively. Results: A total of 117 patients participating in the study. Sixty-six patients in group 1 had SVGD (Mean age: 68,13±8,22, 60,6% male). Fifty-one patients in group 2 did not have SVGD (Mean age: 66,92±9,44, 72,5% male ). The mean CHA2DS2-VASc score was significantly higher in group 1 compared to group 2. [5 (2-7) vs.  2 (1-7), respectively, P<0,001]. As a result of multivariate analysis, CHA2DS2-VASc score (OR: 5,263, CI 95%: 2,176- 12,728, P<0.001) and SII (OR: 1,236, CI 95%: 1,120-2,955, P=0.007) were determined as independent predictors for predicting SVGD Conclusion: In the light of the results we have found, the CHA2DS2-VASc score and SII, which are easy to calculate in daily practice, can help us in predicting SVGD.

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