Diffuse choroidal hemangioma associated with exudative retinal detachment in a Sturge–Weber syndrome case: Photodynamic therapy and intravitreous bevacizumab

Purpose.To report the treatment outcome of photodynamic therapy with verteporfin (PDT) for exudative retinal detachment (RD) associated with diffuse choroidal hemangioma in Sturge-Weber syndrome (SWS).Methods.An interventional case report of a 10-year-old girl with SWS who developed an exudative RD (visual acuity hand motions) that was treated with PDT. She was treated with a first session of multispot PDT. Posteriorly, a choroidotomy for drainage of subretinal fluid was created, combined with an intravitreal injection of gas (SF6) and cryoapplication. Finally, a second session of PDT was applied.Results.Subretinal fluid resolved over a period of one year and visual acuity increased to 20/125.Conclusions.PDT is an effective therapeutic option for exudative RD associated with diffuse choroidal hemangioma.

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Partial thickness sclerectomy to treat exudative retinal detachment secondary a submacular choroidal hemangioma in a Sturge–Weber syndrome

International Ophthalmology ◽

10.1007/s10792-018-1056-2 ◽

2018 ◽

Vol 39 (2) ◽

pp. 491-495

Author(s):

Barbara Parolini ◽

Daniele Cardillo ◽

Andrea Baldi ◽

Attilio Di Salvatore ◽

Alessandro Finzi ◽

...

Keyword(s):

Retinal Detachment ◽

Exudative Retinal Detachment ◽

Choroidal Hemangioma ◽

Partial Thickness ◽

Weber Syndrome ◽

Sturge Weber Syndrome

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PHOTODYNAMIC THERAPY USING VERTEPORFIN FOR A DIFFUSE CHOROIDAL HEMANGIOMA IN STURGE–WEBER SYNDROME

Retina ◽

10.1097/00006982-200402000-00022 ◽

2004 ◽

Vol 24 (1) ◽

pp. 152-155 ◽

Cited By ~ 17

Author(s):

HARSHIVINDERJIT S. BAINS ◽

ANTHONY C. CIRINO ◽

BENJAMIN H. TICHO ◽

LEE M. JAMPOL

Keyword(s):

Photodynamic Therapy ◽

Choroidal Hemangioma ◽

Weber Syndrome ◽

Sturge Weber Syndrome ◽

Diffuse Choroidal Hemangioma

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Photodynamic therapy for diffuse choroidal hemangioma in a child with Sturge-Weber syndrome

Journal of American Association for Pediatric Ophthalmology and Strabismus ◽

10.1016/j.jaapos.2014.10.032 ◽

2015 ◽

Vol 19 (2) ◽

pp. 181-183 ◽

Cited By ~ 7

Author(s):

Ryan Nugent ◽

Lawrence Lee ◽

Anthony Kwan

Keyword(s):

Photodynamic Therapy ◽

Choroidal Hemangioma ◽

Weber Syndrome ◽

Sturge Weber Syndrome ◽

Diffuse Choroidal Hemangioma

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Choroidal thickness changes with photodynamic therapy for a diffuse choroidal hemangioma in Sturge–Weber syndrome

International Ophthalmology ◽

10.1007/s10792-014-9933-9 ◽

2014 ◽

Vol 34 (5) ◽

pp. 1131-1135 ◽

Cited By ~ 12

Author(s):

Andrea Cacciamani ◽

Fabio Scarinci ◽

Mariacristina Parravano ◽

Paola Giorno ◽

Monica Varano

Keyword(s):

Photodynamic Therapy ◽

Choroidal Thickness ◽

Choroidal Hemangioma ◽

Weber Syndrome ◽

Sturge Weber Syndrome ◽

Diffuse Choroidal Hemangioma

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Ruthenium-106 Plaque Therapy for Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome

Case Reports in Ophthalmological Medicine ◽

10.1155/2011/785686 ◽

2011 ◽

Vol 2011 ◽

pp. 1-3 ◽

Cited By ~ 4

Author(s):

Agnieszka Kubicka-Trząska ◽

Joanna Kobylarz ◽

Bożena Romanowska-Dixon

Keyword(s):

Retinal Detachment ◽

External Beam Radiotherapy ◽

Tumor Thickness ◽

Exudative Retinal Detachment ◽

Therapy Outcomes ◽

Corrected Visual Acuity ◽

Weber Syndrome ◽

Sturge Weber Syndrome ◽

Diffuse Choroidal Hemangioma

Diffuse choroidal hemangiomas associated with Sturge-Weber syndrome (SWS) are classically treated with external beam radiotherapy (EBR), but there are a few reports usually of single cases indicating the usefulness of plaque therapy. We present our observations on two cases of diffuse choroidal hemangiomas with exudative retinal detachment associated with SWS treated with Ruthenium-106 plaque therapy. Outcomes included best-corrected visual acuity (BCVA) and regression in tumor thickness measured by ultrasonography. The initial BCVA of the affected eyes was counting fingers at 1 meter and light projection. Pretreatment tumors thickness was 3.5 mm and 4.7 mm. In a follow-up period of 18–24 months, significant reduction in thickness of choroidal hemangiomas up to 1.2 mm and 1.4 mm with prompt resolution of exudative retinal detachment was observed. BCVA achieved 20/200 and 20/400, respectively. The findings in this paper indicate that Ruthenium-106 plaque therapy is effective in treatment of diffuse choroidal hemangiomas associated with SWS.

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