A versatile ring-closure method for efficient synthesis of cyclic polymer and tadpole-shaped copolymer

Polymer ◽  
2021 ◽  
pp. 124314
Author(s):  
Hualong Zhang ◽  
Wen Xu ◽  
Zhigang Wu ◽  
Chao Liu ◽  
Chunyan Hong
2004 ◽  
Vol 116 (7) ◽  
pp. 884-886 ◽  
Author(s):  
Poonsakdi Ploypradith ◽  
Chulabhorn Mahidol ◽  
Poolsak Sahakitpichan ◽  
Siriporn Wongbundit ◽  
Somsak Ruchirawat

2019 ◽  
Vol 43 (1-2) ◽  
pp. 14-19
Author(s):  
Shuting Li ◽  
Wanfeng Yang ◽  
Min Ji ◽  
Jin Cai ◽  
Junqing Chen

A new and efficient synthesis of 6-bromo-8-cyclopentyl-5-methyl-2-(methylsulfinyl)-pyrido[2,3-d]pyrimidin-7(8H)-one, a key intermediate of Palbociclib, starting from thiouracil was described. This protocol involved methylation, nucleophilic substitution, bromination, nucleophilic substitution, Heck reaction, ring closure, oxidation, and bromination to afford a key intermediate of Palbociclib with approximately 35% overall yield. The advantages of this developed synthetic strategy included improved overall yield, inexpensive starting materials, and readily controllable and cleaner reaction conditions.


2020 ◽  
Vol 11 (14) ◽  
pp. 3586-3591 ◽  
Author(s):  
Guofeng Li ◽  
Man Zhao ◽  
Junqiu Xie ◽  
Ying Yao ◽  
Lingyun Mou ◽  
...  

Novel 10π-electron cyclic amidines with excellent fluorescence properties were synthesized by a general and efficient 6π-electrocyclic ring closure of ketenimine and imine starting from N-sulfonyl triazoles and arylamines.


2014 ◽  
Vol 47 (12) ◽  
pp. 3775-3781 ◽  
Author(s):  
Qingquan Tang ◽  
Ying Wu ◽  
Peng Sun ◽  
Yongming Chen ◽  
Ke Zhang

2003 ◽  
Vol 42 (36) ◽  
pp. 4373-4375 ◽  
Author(s):  
Olivier David ◽  
Wim J. N. Meester ◽  
Hans Bieräugel ◽  
Hans E. Schoemaker ◽  
Henk Hiemstra ◽  
...  

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