Synthesis of triaryls: hydroxy and amine dinaphthyl and diphenanthryl aryls by one-pot electron-transfer nucleophilic substitution reactions

Tetrahedron ◽  
2014 ◽  
Vol 70 (22) ◽  
pp. 3614-3620 ◽  
Author(s):  
Liliana B. Jimenez ◽  
Natalia V. Torres ◽  
José L. Borioni ◽  
Adriana B. Pierini
Keyword(s):  
Electron Transfer ◽  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
One Pot ◽  
Nucleophilic Substitution Reactions

scholarly journals A Synthesis of 4-Chloro-2-(trichloromethyl)pyrimidines and Their Study in Nucleophilic Substitution

Synthesis ◽  
2018 ◽  
Vol 51 (02) ◽  
pp. 530-537 ◽  
Author(s):  
Moisés Romero-Ortega ◽  
Michelle Trujillo-Lagunas ◽  
Ignacio Medina-Mercado ◽  
Ivann Zaragoza-Galicia ◽  
Horacio Olivo
Keyword(s):  
Nucleophilic Substitution ◽  
Intramolecular Cyclization ◽  
Nitrogen Heterocycles ◽  
Cyclization Reaction ◽  
Substitution Reactions ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Acyl Chlorides ◽  
Nucleophilic Substitution Reactions ◽  
One Pot Synthesis

A convenient two-step, one-pot synthesis of 4-chloro-2-(trichloromethyl)pyrimidines starting from 2-(trichloromethyl)-1,3-diazabutadienes is described. These nitrogen heterocycles were prepared by a sequential acylation/intramolecular cyclization reaction between 2-(trichloromethyl)-1,3-diazabutadienes and acyl chlorides in the presence of triethylamine followed by treatment with POCl3. This is the first report for the synthesis of this type of 4-chloro-2-(trichloromethyl)pyrimidine derivatives and serves as a source for a wide variety of other substituted pyrimidines by nucleophilic substitution reactions.

Nucleophilic Substitution Reactions by Electron Transfer

ChemInform ◽  
2003 ◽  
Vol 34 (17) ◽  
Author(s):  
Roberto A. Rossi ◽  
Adriana B. Pierini ◽  
Alicia B. Penenory
Keyword(s):  
Electron Transfer ◽  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions
Sign in / Sign up

Export Citation Format

Share Document