Increased platelet glycoprotein IIb/IIIa activation precedes continuous-flow left ventricular assist device pump thrombosis events

2021 ◽  
Author(s):  
Matthew Weiland ◽  
Jennifer Schuitema ◽  
Stefan Jovinge ◽  
Sangjin Lee
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Continuous Flow ◽  
Left Ventricular ◽  
Platelet Glycoprotein ◽  
Assist Device ◽  
Ventricular Assist ◽  
Pump Thrombosis ◽  
Left Ventricular Assist

Pump Thrombosis

2019 ◽  
pp. 281-290
Author(s):  
Jacob N. Schroder ◽  
Carmelo A. Milano
Keyword(s):  
Postoperative Complication ◽  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Continuous Flow ◽  
Treatment Strategies ◽  
Left Ventricular ◽  
Assist Device ◽  
Ventricular Assist ◽  
Pump Thrombosis ◽  
Left Ventricular Assist

This chapter reviews the mechanisms, diagnosis, and treatment strategies of left ventricular assist device (LVAD) thrombosis. Despite improving results, thrombosis continues to be an important postoperative complication of continuous-flow (CF) LVADs. When LVAD thrombosis is suspected, aggressive and timely evaluation and treatment is critical. This chapter also reviews data on newer generation LVADs which appear to be more hemocompatible, reducing the risk of thrombosis.

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