Renal Function Improvement After Conversion to Proliferation Signal Inhibitors During Long-Term Follow-up in Heart Transplant Recipients

2012 ◽  
Vol 44 (9) ◽  
pp. 2564-2566 ◽  
Author(s):  
E. Kaplinsky ◽  
J. González-Costello ◽  
N. Manito ◽  
J. Roca ◽  
M.J. Barbosa ◽  
...  
Keyword(s):  
Renal Function ◽  
Heart Transplant ◽  
Transplant Recipients ◽  
Long Term Follow Up ◽  
Proliferation Signal Inhibitors ◽  
Heart Transplant Recipients

Determinants of Renal Function in Pediatric Heart Transplant Recipients: Long-term Follow-up Study

2007 ◽  
Vol 26 (2) ◽  
pp. 108-113 ◽  
Author(s):  
Ritu Sachdeva ◽  
Richard T. Blaszak ◽  
Kathryn A. Ainley ◽  
James G. Parker ◽  
William R. Morrow ◽  
...  
Keyword(s):  
Renal Function ◽  
Heart Transplant ◽  
Transplant Recipients ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
Heart Transplant Recipients ◽  
Pediatric Heart Transplant

Long-term follow-up of lung and heart transplant recipients with pre-transplant malignancies

2012 ◽  
Vol 31 (12) ◽  
pp. 1276-1280 ◽  
Author(s):  
Vilborg Sigurdardottir ◽  
Oystein Bjortuft ◽  
Hans Eiskjær ◽  
Bjorn Ekmehag ◽  
Einar Gude ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Transplant Recipients ◽  
Long Term Follow Up ◽  
Heart Transplant Recipients

scholarly journals Long Term Follow-up of Heart Transplant Recipients Treated for Acute Allograft Rejection with Methotrexate and/or OKT3

1998 ◽  
Vol 65 (12) ◽  
pp. S157
Author(s):  
G. Martin Mullen ◽  
Marc A. Silver ◽  
Krystyna Malinowska ◽  
Christine E. Lawless ◽  
Jose Mendez ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Allograft Rejection ◽  
Transplant Recipients ◽  
Acute Allograft Rejection ◽  
Long Term Follow Up ◽  
Heart Transplant Recipients

scholarly journals Long-Term Efficacy and Safety of Conversion to Tacrolimus in Heart Transplant Recipients with Ongoing or Recurrent Acute Cellular Rejection

2010 ◽  
pp. 379-384
Author(s):  
B Skalická ◽  
I Málek ◽  
M Kubánek ◽  
J Vymětalová ◽  
J Kautzner
Keyword(s):  
Cyclosporine A ◽  
Heart Transplant ◽  
Acute Cellular Rejection ◽  
Efficacy And Safety ◽  
Transplant Recipients ◽  
Long Term Follow Up ◽  
Heart Transplant Recipients ◽  
Cellular Rejection

Despite the widespread use of potent immunosuppressive drugs, such as cyclosporin A and mycophenolate mofetil, ongoing and recurrent cellular rejection remain a common problem after heart transplantation. We aimed to describe the long-term effects of conversion from cyclosporine A to tacrolimus in patients with ongoing and recurrent cellular rejection. This was a single-centre retrospective analysis of 17 heart transplant recipients who were switched from cyclosporine A to tacrolimus due to ongoing (5 patients) or recurrent cellular rejection (12 patients). We studied long-term efficacy and safety of this approach. 167 endomyocardial biopsies were performed during a mean followup of 69.1±12.7 months. Thirteen biopsies (7.8 %) in eight patients (47 %) revealed higher grades of acute cellular rejection (Banff 2). However, they were not hemodynamically significant and did not require intravenous antirejection therapy. The mean rejection score was reduced significantly. Conversion to tacrolimus was tolerated in 82 % pts without any significant side effects during a long-term follow-up. In conclusion, the conversion to tacrolimus in heart transplant recipients with ongoing or recurrent acute cellular rejection was safe and effective also during a long-term follow-up.

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