Juxtaglomerular Cell Tumor: a Rare Presentation of a Surgically Curable Cause of Secondary Hypertension in the Pediatric Population

Urology ◽  
2021 ◽  
Author(s):  
Corey Phillis ◽  
Eric Midenberg ◽  
Matthews O'Connor ◽  
William Terry ◽  
Christopher Keel ◽  
...  
Genes ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 220
Author(s):  
Jan Papez ◽  
Jiri Starha ◽  
Pavel Zerhau ◽  
Denisa Pavlovska ◽  
Marta Jezova ◽  
...  

Spindle cell hemangioma is a benign vascular tumor typically occurring in the dermis or subcutis of distal extremities as red–brown lesions that can grow in both size and number over time. They can be very painful and potentially disabling. A family history of cancer or previous history may be relevant and must be taken into consideration. Juxtaglomerular cell tumor (reninoma) is an extremely rare cause of secondary hypertension diagnosed mostly among adolescents and young adults. Excessive renin secretion results in secondary hyperaldosteronism. Subsequent hypokalemia and metabolic alkalosis, together with high blood pressure, are clues for clinical diagnosis. Histological examination of the excised tumor leads to a definitive diagnosis. Reninoma is found in subcapsular localization, in most cases as a solitary mass, in imaging studies of kidneys. Exceptionally, it can be located in another part of a kidney. Both spindle cell hemangioma and reninoma are extremely rare tumors in children and adolescents. Herein, the authors present a case report of a patient with hereditary BRCA1 interacting protein C-terminal helicase 1 (BRIP1) mutation, spindle cell hemangioma, and secondary hypertension caused by atypically localized reninoma.


2010 ◽  
Vol 109 (3) ◽  
pp. 237-240 ◽  
Author(s):  
Shih-Yi Lin ◽  
Wayne-Young Liu ◽  
Wen-Chi Chen ◽  
Rong-Hsing Chen

2005 ◽  
Vol 94 (6) ◽  
pp. 1143-1145
Author(s):  
Kouichi Fujita ◽  
Naoto Yoneda ◽  
Yasuyuki Kurimoto ◽  
Hirohide Yoshimura ◽  
Atsuko Morimoto ◽  
...  

2018 ◽  
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pp. 637-640 ◽  
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Igor Nunes ◽  
Tiago Santos ◽  
Joana Tavares ◽  
Lurdes Correia ◽  
João Coutinho ◽  
...  

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Vol 14 (3) ◽  
pp. 108 ◽  
Author(s):  
Kyoung Hee Kim ◽  
Eun Ju Cho ◽  
Byoung Soo Jie ◽  
So Young Lee ◽  
Chong Jin Kim ◽  
...  

2021 ◽  
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Takashi Ueda ◽  
Yukiko Morinaga ◽  
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Sojiro Hirano ◽  
Hiroki Matsubara ◽  
...  

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Vol 28 (8) ◽  
pp. 1098-1102 ◽  
Author(s):  
Xiuzhen Duan ◽  
Patrick Bruneval ◽  
Rasheed Hammadeh ◽  
Raoul Fresco ◽  
John N Eble ◽  
...  

2020 ◽  
pp. 164-165
Author(s):  
Anna Caliò ◽  
Diego Segala ◽  
Guido Martignoni

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