Evaluation of the potential of synthetic peptides of 80kDa human sperm antigen (80kDaHSA) for the development of contraceptive vaccine for male

Vaccine ◽  
2008 ◽  
Vol 26 (29-30) ◽  
pp. 3711-3718 ◽  
Author(s):  
Bharati Gangaram Khobarekar ◽  
Vandana Vernekar ◽  
Vijaya Raghavan ◽  
Masaharu Kamada ◽  
Masahiko Maegawa ◽  
...  
Keyword(s):  
Synthetic Peptides ◽  
Human Sperm ◽  
Contraceptive Vaccine ◽  
Sperm Antigen

Studies with Synthetic Peptides of 80 kDa Human Sperm Antigen (80 kDa HSA)

2004 ◽  
Vol 51 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Vandana J. Vernekar ◽  
A. H. Bandivdekar ◽  
Vijaya P. Raghavan ◽  
M. Kamada ◽  
S. S. Koide
Keyword(s):  
Synthetic Peptides ◽  
Human Sperm ◽  
Sperm Antigen

Biochemical and MALDI Analysis of the Human Sperm Antigen gp20, Homologue of Leukocyte CD52

1999 ◽  
Vol 258 (3) ◽  
pp. 639-643 ◽  
Author(s):  
Riccardo Focarelli ◽  
Cinzia Della Giovampaola ◽  
Roberta Seraglia ◽  
Cecilia Brettoni ◽  
Laura Sabatini ◽  
...  
Keyword(s):  
Human Sperm ◽  
Maldi Analysis ◽  
Sperm Antigen

scholarly journals Expression of gp20, a human sperm antigen of epididymal origin, is reduced in spermatozoa from subfertile men

2004 ◽  
Vol 69 (2) ◽  
pp. 235-240 ◽  
Author(s):  
V. Giuliani ◽  
C. Pandolfi ◽  
R. Santucci ◽  
F. Pelliccione ◽  
B. Macerola ◽  
...  
Keyword(s):  
Human Sperm ◽  
Sperm Antigen

Native zona pellucida reactivity and in-vitro effect on human sperm–egg binding with antisera against bonnet monkey ZP1 and ZP3 synthetic peptides

2002 ◽  
Vol 56 (1-2) ◽  
pp. 77-91 ◽  
Author(s):  
Neela Sivapurapu ◽  
Abhishek Upadhyay ◽  
Akiko Hasegawa ◽  
Koji Koyama ◽  
Satish K Gupta
Keyword(s):  
Zona Pellucida ◽  
Synthetic Peptides ◽  
Human Sperm ◽  
Bonnet Monkey ◽  
Vitro Effect

scholarly journals Oral Immunization with Attenuated Salmonella Expressing Human Sperm Antigen Induces Antibodies in Serum and the Reproductive Tract1

1995 ◽  
Vol 53 (2) ◽  
pp. 462-471 ◽  
Author(s):  
Jay Srinivasan ◽  
Steven Tinge ◽  
Riechard Wright ◽  
John C. Herr ◽  
Roy Curtiss
Keyword(s):  
Human Sperm ◽  
Oral Immunization ◽  
Sperm Antigen

scholarly journals Human sperm carbohydrate antigens defined by an antisperm human monoclonal antibody derived from an infertile woman bearing antisperm antibodies in her serum.

1988 ◽  
Vol 168 (1) ◽  
pp. 343-356 ◽  
Author(s):  
Y Tsuji ◽  
H Clausen ◽  
E Nudelman ◽  
T Kaizu ◽  
S Hakomori ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Human Monoclonal Antibody ◽  
Human Sperm ◽  
Infertile Woman ◽  
Antisperm Antibodies ◽  
Infertile Women ◽  
Epitope Structure ◽  
Sperm Immobilization ◽  
Sperm Antigen

The epitope structure of the human sperm antigen reacting with antibodies present in sera of infertile women has been studied using mAb H6-3C4, which produces immobilization of human sperm in the presence of complement. Another antibody, NUH2, which also induces human sperm immobilization, was used to substantiate the presence of a receptor on sperm involved in susceptibility to immobilization. Both antibodies defined type 2 chain polylactosamine structure. H6-3C4 is directed to internally located repetitive N-acetyllactosamine, i.e., sialyl-i, i, or fucosyl-i. NUH2 defines binary alpha 2----3 sialyl type 2 chain, i.e., sialyl-I. Thus, the presence of antibodies in the sera of infertile women directed to sperm lactosaminoglycan or lactosaminolipid could be the basis for infertility in these cases.

scholarly journals Molecular Cloning and Characterization of a Novel Human Sperm Antigen (HE2) Specifically Expressed in the Proximal Epididymis1

1994 ◽  
Vol 50 (3) ◽  
pp. 516-525 ◽  
Author(s):  
Caroline Osterhoff ◽  
Christiane Kirchhoff ◽  
Nora Krull ◽  
Richard Ivell
Keyword(s):  
Molecular Cloning ◽  
Human Sperm ◽  
Sperm Antigen
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