A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

2012 ◽  
Vol 2012 ◽  
pp. 17-18
Author(s):  
R.S. Panush
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Monoclonal Antibody ◽  
Lupus Erythematosus ◽  
B Lymphocyte ◽  
Phase Iii ◽  
Controlled Study ◽  
Systemic Lupus ◽  
B Lymphocyte Stimulator

Alopecia areata in patients with systemic lupus erythematosus treated with belimumab: a plausible association

Lupus ◽  
2020 ◽  
Vol 29 (4) ◽  
pp. 426-430 ◽  
Author(s):  
O Shamriz ◽  
S H Yahia ◽  
Y Ramot ◽  
N Agmon-Levin ◽  
Y Tal
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Monoclonal Antibody ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Lupus Erythematosus ◽  
B Lymphocyte ◽  
Systemic Lupus ◽  
Immune Mediated ◽  
B Lymphocyte Stimulator ◽  
Current Report

Belimumab, an anti-B-lymphocyte stimulator monoclonal antibody, was recently approved for the treatment of systemic lupus erythematosus. Alopecia areata is characterized by an acute immune-mediated hair loss. Herein, we report on three adult systemic lupus erythematosus patients who developed alopecia areata in association with belimumab treatment. Alopecia areata was resolved in all three patients and belimumab was discontinued in two of them. Thus, in the current report, we explore the plausible link between alopecia areata and belimumab.

scholarly journals B lymphocyte stimulator expression in pediatric systemic lupus erythematosus and juvenile idiopathic arthritis patients

2009 ◽  
Vol 60 (11) ◽  
pp. 3400-3409 ◽  
Author(s):  
Sandy D. Hong ◽  
Andreas Reiff ◽  
Hai-Tao Yang ◽  
Thi-Sau Migone ◽  
Christopher D. Ward ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Juvenile Idiopathic Arthritis ◽  
Lupus Erythematosus ◽  
B Lymphocyte ◽  
Systemic Lupus ◽  
Pediatric Systemic Lupus Erythematosus ◽  
B Lymphocyte Stimulator

scholarly journals B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations

2003 ◽  
Vol 48 (12) ◽  
pp. 3475-3486 ◽  
Author(s):  
William Stohl ◽  
Samy Metyas ◽  
Soon-Min Tan ◽  
Gurtej S. Cheema ◽  
Bonifacia Oamar ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
B Lymphocyte ◽  
Systemic Lupus ◽  
B Lymphocyte Stimulator
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