Prognostic indicators in the prenatal diagnosis of agenesis of corpus callosum

1994 ◽  
Vol 170 (3) ◽  
pp. 753-758 ◽  
Author(s):  
Patrizia Vergani ◽  
Alessandro Ghidini ◽  
Nicola Strobelt ◽  
Anna Locatelli ◽  
Silvana Mariani ◽  
...  
Author(s):  
Marta Kacprzak ◽  
Hanna Moczulska ◽  
Marta Chrzanowska ◽  
Piotr Sieroszewski

2006 ◽  
Vol 48 (3) ◽  
pp. 298-304 ◽  
Author(s):  
PISANI FRANCESCO ◽  
BIANCHI MARIA-EDGARDA ◽  
PIANTELLI GIOVANNI ◽  
GRAMELLINI DANDOLO ◽  
BEVILACQUA GIULIO

2020 ◽  
Vol 41 (6) ◽  
pp. 1521-1529 ◽  
Author(s):  
Ayşe Kaçar Bayram ◽  
Mehmet Serdar Kütük ◽  
Selim Doganay ◽  
Mahmut Tuncay Özgün ◽  
Hakan Gümüş ◽  
...  

2021 ◽  
pp. 1-8
Author(s):  
Sara Bernardes da Cunha ◽  
Maria Carolina Carneiro ◽  
Maria Miguel Sa ◽  
Andrea Rodrigues ◽  
Carla Pina

Abnormalities of corpus callosum are one of the most common brain anomalies. Fetuses with isolated corpus callosum agenesis (CCA) have a better prognosis than those with additional anomalies. However, unpredictable neurodevelopmental outcomes of truly isolated CCA make prenatal counseling a challenge. The aim of this review is to evaluate neurodevelopmental outcomes in children with prenatal diagnosis of isolated CCA. Controlled clinical trials published between May 23, 2009, and May 23, 2019, using the MeSH term “agenesis of corpus callosum” were reviewed. A total of 942 articles were identified, and 8 studies were included in the systematic review depending on the inclusion criteria. These studies included 217 fetuses with isolated CCA and no other anomalies at prenatal assessment. Neurodevelopmental outcome was reported to be normal in 83 children with a prenatal diagnosis of isolated CCA confirmed at birth within 128 completed assessments. About 45 children presented borderline, moderate, or severe neurodevelopmental outcome. In this review, neurodevelopment was favorable in two-thirds of the cases, but mild disabilities emerged in older children. Despite this, disabilities can occur later beyond school age and a low risk of severe cognitive impairment exists. Our study highlights the essential early diagnosis and proper supportive therapy.


Pteridines ◽  
2014 ◽  
Vol 25 (3-4) ◽  
Author(s):  
Tanya Kitova ◽  
Borislav Kitov ◽  
Denis Milkov ◽  
Nahed Ben Cheikh ◽  
Soumeya Gaigi

AbstractThe aim of this study was to draw the attention of specialists faced with fetal hydrocephalus in the postnatal period to the possibilities of prenatal diagnosis and further monitoring by studying isolated and syndrome cases in fetuses. One hundred and nine fetuses from a total of 2238 autopsies were the subject of observation in this study. In 64 (58.7%) of the studied fetuses, isolated hydrocephalus was found, while the other 45 cases were associated with the following malformations: Arnold-Chiari type II, Dandy-Walker, stenosis of the aqueductus sylvii, agenesis of corpus callosum (partial and total) and numerical chromosomal aberrations such as trisomy 13, 15 and 18. In cases of isolated hydrocephalus and a stable condition of the fetus, it is possible to wait until the term, or to induce labor without danger to the child, followed by a shunting intervention.


2003 ◽  
Vol 19 (7-8) ◽  
pp. 471-476 ◽  
Author(s):  
Marie-Laure Moutard ◽  
Virginie Kieffer ◽  
Josué Feingold ◽  
François Kieffer ◽  
Fanny Lewin ◽  
...  

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