Intraaortic Balloon Counterpulsation: Its Influence Alone and Combined with Various Pharmacological Agents on Regional Myocardial Blood Flow during Experimental Acute Coronary Occlusion

1981 ◽  
Vol 31 (2) ◽  
pp. 144-154 ◽  
Author(s):  
G. Kimble Jett ◽  
Satish K. Dengle ◽  
Peggy A. Barnett ◽  
Melvin R. Platt ◽  
James T. Willerson ◽  
...  
Keyword(s):  
Blood Flow ◽  
Myocardial Blood Flow ◽  
Coronary Occlusion ◽  
Regional Myocardial Blood Flow ◽  
Intraaortic Balloon ◽  
Pharmacological Agents ◽  
Acute Coronary Occlusion ◽  
Intraaortic Balloon Counterpulsation ◽  
Balloon Counterpulsation ◽  
Regional Myocardial Blood

scholarly journals Contrast echocardiographic estimation of regional myocardial blood flow after acute coronary occlusion.

Circulation ◽  
1985 ◽  
Vol 72 (5) ◽  
pp. 1115-1124 ◽  
Author(s):  
A J Kemper ◽  
T Force ◽  
R Kloner ◽  
M Gilfoil ◽  
L Perkins ◽  
...  
Keyword(s):  
Blood Flow ◽  
Myocardial Blood Flow ◽  
Coronary Occlusion ◽  
Regional Myocardial Blood Flow ◽  
Acute Coronary Occlusion ◽  
Regional Myocardial Blood

Depression of regional blood flow and wall thickening after brief coronary occlusions

1978 ◽  
Vol 234 (6) ◽  
pp. H653-H659 ◽  
Author(s):  
G. R. Heyndrickx ◽  
H. Baig ◽  
P. Nellens ◽  
I. Leusen ◽  
M. C. Fishbein ◽  
...  
Keyword(s):  
Blood Flow ◽  
Myocardial Blood Flow ◽  
Coronary Occlusion ◽  
Reactive Hyperemia ◽  
Left Ventricular ◽  
Regional Myocardial Blood Flow ◽  
Wall Thickening ◽  
Flow Ratio ◽  
Systolic Wall Thickening ◽  
Regional Myocardial Blood

The effects of a 15-min coronary occlusion and subsequent reperfusion were investigated in conscious dogs previously instrumented for measurement of left ventricular pressure, dP/dt, regional wall thickening, electrograms, and myocardial blood flow. Coronary occlussion reduced overall left ventricular function only slightly but eliminated systolic wall thickening in the ischemic zone and reduced regional myocardial blood flow in the ischemic zone from 1.04 +/- 0.04 to 0.27 +/- 0.02 ml/min per g and the endo/epi flow ratio from 1.23 +/- 0.04 to 0.44 +/- 0.04, while S-T segment elevation increased from 1.1 +/- 0.3 to 8.2 +/- 0.9 mV. After release of the occlusion, S-T segment elevation disappeared within 1 min while reactive hyperemia in the previously occluded artery and a transient increase in cardiac diastolic wall thickness occurred and then subsided by 15 min. In contrast, systolic wall thickening and the endo/epi flow ratio remained significantly depressed for more than 3 h. Thus reperfusion after a 15 minute coronary occlusion results in a prolonged period of reduced regional myocardial blood flow, particularly in the endocardial layers, which correlates with the prolonged depression of regional myocardial shortening and wall thickening.

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