Choroidal neovascularization following argon laser photocoagulation for macular edema associated with branch retinal vein obstruction

2000 ◽  
Vol 35 (7) ◽  
pp. 427-430 ◽  
Author(s):  
Gaurav K. Shah ◽  
Sanjay Sharmaj ◽  
Gary C. Brown
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins

The Early Treatment Diabetic Retinopathy Study (ETDRS) was a randomized clinical trial involving nearly four thousand diabetic patients with early proliferative retinopathy, moderate to severe nonproliferative retinopathy, and/or diabetic macular edema in each eye. This paper (ETDRS report number 1) describes the findings in the subgroup of eyes in the ETDRS that were identified as having mild to moderate nonproliferative diabetic retinopathy and macular edema. The analysis showed that immediate focal argon laser photocoagulation of “clinically significant” diabetic macular edema substantially reduced the risk of visual loss, increased the chance of visual improvement, decreased the frequency of persistent macular edema, and caused only minor visual field losses. The authors recommended immediate focal argon laser photocoagulation for all eyes with clinically significant macular edema and mild or moderate nonproliferative diabetic retinopathy, regardless of the level of visual acuity.


2018 ◽  
Vol 196 ◽  
pp. xxx-xxxviii
Author(s):  
John G. Clarkson ◽  
J. Donald M. Gass ◽  
Victor T. Curtin ◽  
Edward W.D. Norton ◽  
George W. Blankenship ◽  
...  

Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins

The Branch Vein Occlusion Study (BVOS) was a randomized, incompletely masked, controlled clinical trial in patients with a branch retinal vein occlusion (BRVO) occurring 3 to 18 months earlier, with best corrected visual acuity of 20/40 or worse from macular edema. The study showed that argon laser grid photocoagulation could improve visual acuity in eyes with BRVO and macular edema reducing visual acuity to 20/40 or worse. After this study, grid photocoagulation of the macula became the standard of care for BRVO with macular edema with foveal involvement and capillary leakage with visual acuity of 20/40 or worse, and it remains the gold standard therapy for perfused macular edema in BRVO. Advantages are that it is proven, widely available, nonsurgical, and of relatively moderate cost.


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