Ultrasound biomicroscopic analysis of drug-induced bilateral angle-closure glaucoma associated with supraciliary choroidal effusion

2003 ◽  
Vol 38 (4) ◽  
pp. 299-302 ◽  
Author(s):  
S. Waheeb ◽  
F. Feldman ◽  
P. Velos ◽  
C.J. Pavlin
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Indra Durai ◽  
Mrunali Mohan Dhavalikar ◽  
Chandran Prem Anand ◽  
Venkatraman Ganesh ◽  
Ramaswami Krishnadas

Purpose. To report two persons with acute, bilateral, and simultaneous angle closure glaucoma in pseudophakia secondary to uveal effusions induced by administration of chlorthalidone.Methods. Case reports.Results. Bilateral shallow anterior chambers and high intraocular pressure with decline in visual acuity were reported in two patients within days of intake of chlorthalidone for systemic hypertension. Gonioscopy confirmed appositional angle closure while choroidal detachment and ciliochoroidal detachment were revealed on ultrasonographic studies. Discontinuing chlorthalidone and institution of aqueous suppressants to reduce IOP and cycloplegics reversed angle closure and glaucoma.Conclusions. Reports of angle closure glaucoma in pseudophakic eyes induced by idiosyncratic reaction to chlorthalidone confirms that osmotic changes in the crystalline lens has no role in the pathogenesis of drug induced glaucoma and reaffirms that glaucoma is secondary to ciliochoroidal detachment and ciliary body rotation and edema.


2011 ◽  
Vol 37 (2) ◽  
pp. 415-417 ◽  
Author(s):  
Raffaele Mancino ◽  
Chiara Varesi ◽  
Angelica Cerulli ◽  
Francesco Aiello ◽  
Carlo Nucci

2015 ◽  
Vol 2015 (1) ◽  
pp. 6 ◽  
Author(s):  
Elliott Yann Ah-kee ◽  
Eric Egong ◽  
Ahad Shafi ◽  
Lik Thai Lim ◽  
James Li Yim

2016 ◽  
Vol 25 (2) ◽  
pp. e99-e105 ◽  
Author(s):  
Rory M. Murphy ◽  
Belal Bakir ◽  
Colm O’Brien ◽  
Janey L. Wiggs ◽  
Louis R. Pasquale

2017 ◽  
Vol 158 (50) ◽  
pp. 1998-2002 ◽  
Author(s):  
András Hári-Kovács ◽  
Judit Soós ◽  
Tamás Gyetvai ◽  
Andrea Facskó ◽  
Mihály Végh

Abstract: Sulpha drugs are widely employed in medicine for various diseases and disorders. During the last several decades, numerous papers had been published on supra ciliary and posterior choroidal effusion likely presenting as an idiosyncratic effect of these drugs especially of acetazolamide. In each publication, the effusion was associated with either an acute angle-closure glaucoma or transitory myopia or both of these as leading symptoms. In the current publication, authors report on two cases where the acetazolamide-induced choroidal effusion was an accidental finding without either a myopic shift in refraction or an acute elevation in intraocular pressure. To our best knowledge, ours is the first report in the literature describing this unusual, “silent” form of a sulpha drug-induced choroidal effusion. Since the choroidal involvement may vary in size and location, and is not necessarily associated with acute glaucoma and myopia, one can assume that a considerable amount of acetazolamide-related ocular side-effects will not be discovered. The above case report aims to draw the attention of other specialities to the need for ophthalmic examination for their patients taking sulpha drugs with acute visual deterioration. Orv Hetil. 2017; 158(50): 1998–2002.


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