Low basal serum cortisol in patients with severe atopic dermatitis: potent topical corticosteroids wrongfully accused

2008 ◽  
Vol 2008 ◽  
pp. 56-57
Author(s):  
B.H. Thiers
Keyword(s):  
Atopic Dermatitis ◽  
Serum Cortisol ◽  
Severe Atopic Dermatitis ◽  
Topical Corticosteroids ◽  
Basal Serum

scholarly journals Low basal serum cortisol in patients with severe atopic dermatitis: potent topical corticosteroids wrongfully accused

2007 ◽  
Vol 156 (5) ◽  
pp. 979-985 ◽  
Author(s):  
I.M. Haeck ◽  
L. Timmer-de Mik ◽  
E.G.W.M. Lentjes ◽  
E. Buskens ◽  
D.J. Hijnen ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Serum Cortisol ◽  
Severe Atopic Dermatitis ◽  
Topical Corticosteroids ◽  
Basal Serum

scholarly journals Low Basal Serum Cortisol in Patients with Severe Atopic Dermatitis: Potent Topical Corticosteroids Wrongfully Accused

Dermatitis ◽  
2008 ◽  
Vol 19 (4) ◽  
pp. 218-238
Author(s):  
Carla A. F. M. Bruijnzeel-Koomen ◽  
Inge Marjet Haeck ◽  
Linda Timmer-de Mik ◽  
Everardus G. W. M. Lentjes ◽  
Erik Buskens ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Serum Cortisol ◽  
Severe Atopic Dermatitis ◽  
Topical Corticosteroids ◽  
Basal Serum

scholarly journals Efficacy and Safety of Baricitinib Combined With Topical Corticosteroids for Treatment of Moderate to Severe Atopic Dermatitis

2020 ◽  
Vol 156 (12) ◽  
pp. 1333 ◽  
Author(s):  
Kristian Reich ◽  
Kenji Kabashima ◽  
Ketty Peris ◽  
Jonathan I. Silverberg ◽  
Lawrence F. Eichenfield ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Severe Atopic Dermatitis ◽  
Efficacy And Safety ◽  
Topical Corticosteroids

Low Risk of Adrenal Insufficiency After Use of Low- to Moderate-Potency Topical Corticosteroids for Children With Atopic Dermatitis

2019 ◽  
Vol 58 (4) ◽  
pp. 406-412
Author(s):  
Ladan Davallow Ghajar ◽  
Lauren K. Wood Heickman ◽  
Mark Conaway ◽  
Alan D. Rogol
Keyword(s):  
Atopic Dermatitis ◽  
Adrenal Insufficiency ◽  
Clinical Evidence ◽  
Signs And Symptoms ◽  
Serum Cortisol ◽  
Low Risk ◽  
Adrenal Suppression ◽  
Adrenal Crisis ◽  
Short Term ◽  
Topical Corticosteroids

Our objective was to assess the risk of adrenal insufficiency (AI) with short-term use of low- to moderate-potency topical corticosteroids (TCS) for treatment of atopic dermatitis. Our systematic literature search revealed 9 studies (n = 371) that evaluated AI using adrenocorticotropic hormone stimulation testing, with measures of serum cortisol levels at baseline and following at least 2 weeks of TCS application. Biochemical AI was defined by a stimulated cortisol level of ≤18.0 µg/dL (~500 nmol/L). The overall proportion of AI with low-to-moderate TCS use was 2.7% (95% confidence interval = 1.47% to 4.89%). None of the children showed any clinical evidence of AI or adrenal crisis. Short-term use of low- to moderate-potency TCS for the treatment of atopic dermatitis is associated with a low risk of adrenal suppression. General practitioners do not need to test these patients for adrenal suppression in the absence of concerning signs and symptoms of AI.

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