Intratympanic Gentamicin for Meniere's Disease

1995 ◽  
Vol 112 (5) ◽  
pp. P176-P176
Author(s):  
Loren J. Bartels ◽  
Jonathon S. Sillman

Educational objectives: To comprehensively evaluate patients with Meniere's disease and determine their candidacy for gentamicin therapy and to administer intratympanic gentamicin for the treatment of vertico in Meniere's disease.

2015 ◽  
Vol 129 (10) ◽  
pp. 970-973 ◽  
Author(s):  
G J Watson ◽  
C Nelson ◽  
R M Irving

AbstractBackground:Since the development of intratympanic aminoglycoside in the 1950s, otologists have been able to chemically ablate the vestibule. We present the results of using low-dose intratympanic gentamicin to treat Ménière's disease.Method:A retrospective review was performed of all patients who underwent low-dose intratympanic gentamicin therapy over seven years. Data on gender, age, number of procedures, pure tone audiometry and symptom control were analysed.Results:In all, 38 patients underwent low-dose intratympanic gentamicin therapy. These comprised 25 females and 13 males, with an average age of 58.4 years. Hearing was preserved in 87.5 per cent of patients, with no significant difference before and after treatment (p = 0.744). In all, 85.7 per cent of patients had complete or substantial symptom control (classes A and B, respectively).Conclusion:Low-dose intratympanic gentamicin therapy was effective in controlling the symptoms of Ménière's disease patients, while preserving hearing.


2016 ◽  
Vol 273 (10) ◽  
pp. 3011-3018 ◽  
Author(s):  
Philippe Junet ◽  
Alexandre Karkas ◽  
Georges Dumas ◽  
Jean Louis Quesada ◽  
Sébastien Schmerber

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