Measuring the cochlear blood flow and distortion-product otoacoustic emissions during reversible cochlear ischemia: a rabbit model

1999 ◽  
Vol 133 (1-2) ◽  
pp. 40-52 ◽  
Author(s):  
Thierry Mom ◽  
Fred F. Telischi ◽  
Glen K. Martin ◽  
Brenda L. Lonsbury-Martin
2013 ◽  
Vol 68 (11) ◽  
pp. 94-97
Author(s):  
I. N. D'yakonova ◽  
Yu. S. Ishanova ◽  
I. V. Rakhmanova

Aim: In our chronic experiment to  register changes of acoustic response of Distortion-Product Otoacoustic Emissions (DPOAE) of intact rabbits in postnatal ontogenesis for the purpose of getting normative data which can be used for studying impact of pathological factors on auditory function and maturation of activity of outer hair cell in ontogenesis. Materials and methods: Study of otoacoustic emissions used mature chinchilla rabbits with a 19 day life of up to 3 months. Results: in the course of ripening were obtained functional activity of outer hair cells of the cochlea. Conclusion: normative data obtained allow us to study using a rabbit model, the pathological effects of agents on the maturation of the outer hair cells of the cochlea in the experiment.


2011 ◽  
Vol 2011 ◽  
pp. 1-6
Author(s):  
Ulrich Strassen ◽  
Christoph Deppe ◽  
Klaus Mees ◽  
Nikolaus Plesnila ◽  
Martin Canis ◽  
...  

Distortion product otoacoustic emissions (DPOAEs) have been proposed for monitoring the intracranial pressure (ICP) noninvasively. Aim of this study was to establish an animal model in the guinea pig for a detailed characterisation of ICP-related DPOAE alterations. In guinea pigs, the ICP was elevated experimentally and the DPOAE levels were continuously monitored. Two different patterns of DPOAE level changes were observed: (1) a decrease of few decibels affecting mainly the frequency = 2 kHz with instant recovery after normalization of ICP, probably related to alterations of middle ear sound transmission; (2) a more pronounced level decrease affecting all frequencies, combined with a second decrease and prolonged recovery after ICP normalization, which might be related to alterations of the cochlear blood flow. Alterations of the levels of DPOAEs might not only provide information about ICP but also indicate critical ICP-induced reductions of the cochlear and the cerebral perfusion pressure.


2003 ◽  
Vol 113 (9) ◽  
pp. 1615-1622 ◽  
Author(s):  
Krzysztof Morawski ◽  
Fred F. Telischi ◽  
Faisal Merchant ◽  
Lidet W. Abiy ◽  
Grazyna Lisowska ◽  
...  

2006 ◽  
Vol 2 (1) ◽  
pp. 2-9
Author(s):  
Tiffany A. Johnson ◽  
Stephen T. Neely ◽  
Michael P. Gorga

2013 ◽  
Vol 133 (4) ◽  
pp. EL331-EL337 ◽  
Author(s):  
Makram Zebian ◽  
Volker Schirkonyer ◽  
Johannes Hensel ◽  
Sven Vollbort ◽  
Thomas Fedtke ◽  
...  

1995 ◽  
Vol 97 (4) ◽  
pp. 2359-2377 ◽  
Author(s):  
M. L. Whitehead ◽  
B. B. Stagner ◽  
M. J. McCoy ◽  
B. L. Lonsbury‐Martin ◽  
G. K. Martin

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