scholarly journals Elevated B-type natriuretic peptide in patients with asymptomatic aortic regurgitation and normal left ventricular systolic function

2002 ◽  
Vol 39 ◽  
pp. 423-424
Author(s):  
Micah J. Eimer ◽  
Deborah Ekery ◽  
Vera Rigolin ◽  
Maryl Johnson ◽  
Mihai Gheorghiade ◽  
...  
2016 ◽  
Vol 310 (6) ◽  
pp. H725-H731 ◽  
Author(s):  
Jen-Yuan Kuo ◽  
An-Mei Wang ◽  
Sheng-Hsiung Chang ◽  
Chung-Lieh Hung ◽  
Chun-Yen Chen ◽  
...  

Atrial natriuretic peptide (ANP) secretion increases after 30 min of paroxysmal supraventricular tachycardia (PSVT). Whether this phenomenon also applies to brain or C-type natriuretic peptides (BNP or CNP) remains unknown. Blood samples of 18 patients (41 ± 11 yr old; 4 men) with symptomatic PSVT and normal left ventricular systolic function (ejection fraction 65 ± 6%) were collected from the coronary sinus (CS) and the femoral artery (FA) before and 30 min after the induction, and 30 min after the termination of PSVT. The results showed that the ANP levels rose steeply after the PSVT and then reduced at 30 min after the termination (baseline vs. post-PSVT vs. posttermination: CS: 34.0 ± 29.6 vs. 74.1 ± 42.3 vs. 46.1 ± 32.9; FA: 5.9 ± 3.24 vs. 28.2 ± 20.7 vs. 10.0 ± 4.6 pg/ml; all P < 0.05). In contrast, compared with ANP, the increases of BNP and CNP in CS after the PSVT were less sharp, but continued to rise after the termination of tachycardia (BNP, 10.2 ± 6.4 vs. 11.3 ± 7.1 vs. 11.8 ± 7.9; CNP, 4.5 ± 1.2 vs. 4.9 ± 1.4 vs. 5.0 ± 1.4 pg/ml; all P < 0.05). The rise of BNP and CNP in FA was similarly less sharp after the PSVT and remained stationary after the termination. PSVT exerted differential effects on cardiac natriuretic peptide levels. ANP increased greater after a 30-min induced PSVT, but dropped faster after termination of PSVT, compared with BNP and CNP.


2007 ◽  
Vol 41 (3) ◽  
pp. 155-159 ◽  
Author(s):  
Jen-Yuan Kuo ◽  
Hung-I Yeh ◽  
Sheng-Hsiung Chang ◽  
Bing-Fu Shih ◽  
An-Mei Wang ◽  
...  

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