scholarly journals INTRAVASCULAR ULTRASOUND ASSESSMENT OF MINIMAL STENT AREA AND INTIMAL HYPERPLASIA IN IN–STENT RESTENOSIS AFTER DRUG–ELUTING OR BARE–METAL STENT IMPLANTATION: THE NORDIC INTRAVASCULAR ULTRASOUND STUDY (NIVUS)

2013 ◽  
Vol 61 (10) ◽  
pp. E1801
Author(s):  
Lisette Okkels Jensen ◽  
Saila Vikman ◽  
Lisbeth Antonsen ◽  
Matti Niemela ◽  
Kari Kervinen ◽  
...  
2010 ◽  
Vol 55 (1) ◽  
pp. 135-138 ◽  
Author(s):  
Hiroshi Matsuoka ◽  
Hideo Kawakami ◽  
Akira Ohshita ◽  
Tamami Kohno ◽  
Susumu Shigemi ◽  
...  

2016 ◽  
Vol 31 (6) ◽  
pp. 911-922 ◽  
Author(s):  
Xiangshan Xu ◽  
Lijie Wang ◽  
Guofeng Wang ◽  
Yuanzhe Jin

The coronary artery stent has been widely used in clinic. In-stent restenosis was mainly caused by the excessive proliferation of smooth muscle cell and the inflammation due to the metal ion released from stent scaffold of the drug-eluting stent. Thus, to reduce the in-stent restenosis and promote the vascular endothelialization have become a hot research point in this area. In this paper, a nano-TiO2 ceramic coating was deposited on 316L stainless steel to reduce the metal ion release and to inhibit the inflammation reaction. An endothelia cell selective adhesion peptide Arg-Glu-Asp-Val (REDV) coating was prepared on the ceramic coating by a polydopamine technology to promote the endothelialization. The corrosion test indicated that nano-TiO2 ceramic film could effectively decrease the nickel ion released from 316L stainless steel. REDV/TiO2 coating could promote the endothelial cell adhesion and proliferation, meanwhile REDV/TiO2 coating could also increase the nitric oxide concentration. Bare metal stent, TiO2-coated stent and REDV/TiO2-coated stent were implanted in the iliac arteries of rabbit model. In-stent restenosis and re-endothelialization were evaluated at 28 days post-implantation of the stents. The results showed that REDV/TiO2-coated stents could effectively reduce in-stent restenosis and promote re-endothelialization in comparison with TiO2-coated drug-eluting stent and bare metal stent. These results suggest that REDV/TiO2-coated drug-eluting stent maybe a good choice of the application for coronary artery disease.


2014 ◽  
Vol 63 (12) ◽  
pp. S23
Author(s):  
Takahiro Watanabe ◽  
Kazuhiko Yumoto ◽  
Yoshiyasu Takeda ◽  
Yuichi Hanaki ◽  
Yasutoshi Shinoda ◽  
...  

2018 ◽  
Vol 12 (5) ◽  
pp. 455-463 ◽  
Author(s):  
Ender Ornek ◽  
Mustafa Cetin ◽  
Emrullah Kiziltunc ◽  
Alparslan Kurtul ◽  
Murat Gok ◽  
...  

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