Accumulation of Ca2+ and Sr2+ by rat-liver mitochondria: Preferential loss of the adenosine triphosphate-dependent mechanism for Sr2+ accumulation

Author(s):  
Frank D. Vasington
Nature ◽  
1966 ◽  
Vol 212 (5059) ◽  
pp. 257-258 ◽  
Author(s):  
R. A. REID ◽  
JENNIFER MOYLE ◽  
PETER MITCHELL

1982 ◽  
Vol 204 (1) ◽  
pp. 369-371 ◽  
Author(s):  
Timothy P. Goldstone ◽  
Martin Crompton

The existence of a Na+-dependent mechanism for Ca2+ efflux from isolated rat liver mitochondria was confirmed. The activity of this system is decreased by 60% in mitochondria isolated from perfused livers. The Na+-dependent activity is fully restored by infusion of either 1μm-adrenaline or 1μm-isoprenaline, but the α-adrenergic agonist phenylephrine is ineffective.


Sign in / Sign up

Export Citation Format

Share Document