Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 3: A proposed pharmacophore model for 1-[N-(methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-[4-(substituted)piperidin-1-yl]butanes

2001 ◽  
Vol 11 (18) ◽  
pp. 2469-2473 ◽  
Author(s):  
Paul E. Finke ◽  
Laura C. Meurer ◽  
Bryan Oates ◽  
Shrenik K. Shah ◽  
Jennifer L. Loebach ◽  
...  
Keyword(s):  
Pharmacophore Model ◽  
Ccr5 Receptor ◽  
Anti Hiv ◽  
Human Ccr5 ◽  
Hiv 1

Design, synthesis, and SAR of heterocycle-containing antagonists of the human CCR5 receptor for the treatment of HIV-1 infection

2001 ◽  
Vol 11 (24) ◽  
pp. 3103-3106 ◽  
Author(s):  
Dooseop Kim ◽  
Liping Wang ◽  
Charles G. Caldwell ◽  
Ping Chen ◽  
Paul E. Finke ◽  
...  
Keyword(s):  
Design Synthesis ◽  
Ccr5 Receptor ◽  
Human Ccr5 ◽  
Hiv 1

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 3: polar functionality and its effect on anti-HIV-1 activity

2002 ◽  
Vol 12 (20) ◽  
pp. 2997-3000 ◽  
Author(s):  
Jeffrey J Hale ◽  
Richard J Budhu ◽  
Sander G Mills ◽  
Malcolm MacCoss ◽  
Sandra L Gould ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Ccr5 Receptor ◽  
Anti Hiv ◽  
Hiv 1
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