The features and management of late relapse of nonseminomatous germ cell tumours: The Royal Marsden Experience

2019 ◽  
Vol 18 (4) ◽  
pp. 30
Author(s):  
A.P.M. Jay ◽  
M. Aldiwani ◽  
M.E. O’Callaghan ◽  
A.K. Pearce ◽  
R.A. Huddart ◽  
...  
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours

PD53-04 THE FEATURES AND MANAGEMENT OF LATE RELAPSE OF NON-SEMINOMATOUS GERM CELL TUMOURS

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Alexander Jay ◽  
Mohammed Aldiwani ◽  
Suranga Wijayarathna ◽  
Robert Huddart ◽  
Erik Mayer ◽  
...  
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours

1033 LATE RELAPSE OF TESTICULAR GERM CELL TUMOURS IN 2.729 PATIENTS: A MULTICENTRE ANALYSIS

2011 ◽  
Vol 10 (2) ◽  
pp. 320
Author(s):  
R.J. Hoekstra ◽  
M. Schaapveld ◽  
A.W. Van Den Belt-Dusebout ◽  
R. De Wit ◽  
J.A. Gietema ◽  
...  
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours

Late relapse (>2 years) on surveillance in stage I non-seminomatous germ cell tumours; predominant seminoma only histology

2010 ◽  
Vol 106 (11) ◽  
pp. 1648-1651 ◽  
Author(s):  
Luke Nolan ◽  
Matthew Wheater ◽  
Julie Kirby ◽  
Peter Simmonds ◽  
Graham Mead
Keyword(s):  
Germ Cell ◽  
Stage I ◽  
Late Relapse ◽  
Germ Cell Tumours

Multivariate Analysis of Predictive Factors of Late Relapse in 1264 Patients with Testicular Germ Cell Tumours

2002 ◽  
pp. 273-274
Author(s):  
M. Shahidi ◽  
A. R. Norman ◽  
J. Nicholls ◽  
D. P. Dearnaley ◽  
A. Horwich ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Germ Cell ◽  
Predictive Factors ◽  
Late Relapse ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours

Late relapse of testicular germ cell tumours

2003 ◽  
Vol 2 (1) ◽  
pp. 52
Author(s):  
P. Albers ◽  
M. Lipphardt ◽  
S.C. Müller
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours

Late relapse of nonseminomatous germ cell tumours

2009 ◽  
Vol 104 (9b) ◽  
pp. 1413-1417 ◽  
Author(s):  
Jan Oldenburg ◽  
Sophie D. Fosså
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours

LATE RELAPSE OF TESTICULAR GERM-CELL TUMOURS AFTER RADIOTHERAPY

The Lancet ◽  
1985 ◽  
Vol 326 (8464) ◽  
pp. 1125 ◽  
Author(s):  
R.E. Taylor ◽  
R.T.D. Oliver
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours

scholarly journals Late Relapse and Follow-up Protocols in Testicular Germ Cell Tumours: The Edinburgh Cancer Centre Experience and Review of the Literature

2008 ◽  
Vol 2 ◽  
pp. CMO.S321
Author(s):  
Beatrice Detti ◽  
Paul A. Elliott ◽  
Duncan B. Mclaren ◽  
Grahame C.W. Howard
Keyword(s):  
Germ Cell ◽  
Combined Treatment ◽  
Late Relapse ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Cancer Centre ◽  
Testicular Germ Cell Tumours ◽  
Small Series ◽  
Complete Surgical Excision

Aims To identify clinicopathological features and outcomes in patients with late relapse (LR) of testicular germ cell tumours (GCTs) in order to guide follow-up policy. Materials and Methods The Edinburgh Cancer Centre (ECC) database identified all patients diagnosed with testicular GCT between 1988 and 2002. Of 703 patients, six relapsed more than 24 months after their initial treatment. A retrospective casenote review was performed to extract clinical, pathological, treatment and outcome data. Results Six patients (0.85%) underwent late relapse. All patients presented initially with stage I disease and five were classified as good risk (International Germ Cell Consensus Classification, IGCCC). Median time to LR was 31 months. Two patients had previously relapsed less than 24 months from initial diagnosis. Markers at the time of relapse were normal in all patients. In all cases of late relapse disease was confined to axial lymphadenopathy. Three patients were treated with chemotherapy alone, two patients underwent surgical resection and one patient received combined treatment. All patients obtained a complete response and all remain disease free with a median follow-up of 52 months. Conclusions The incidence of late relapse in this series is low. Chemo-naive patients with LR were successfully salvaged with chemotherapy alone and patients previously exposed to cisplatin-based chemotherapy were salvaged with complete surgical excision. The optimal length of follow-up in patients with testicular germ cell tumours is not known and practice varies widely. In this cohort of 703 patients, only one patient who relapsed was picked up by additional clinic follow-up between 5 and 10 years. Thus, on the basis of this small series, the authors suggest that follow-up after five years may not be justified.

The features and management of late relapse of non-seminomatous germ cell tumours

2017 ◽  
Vol 16 (3) ◽  
pp. e1907-e1908
Author(s):  
A. Jay ◽  
M. Aldiwani ◽  
S. Wijayarathna ◽  
R. Huddart ◽  
E. Mayer ◽  
...  
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours

Late relapse of metastatic non-seminomatous testicular germ cell tumours

2006 ◽  
Vol 61 (11) ◽  
pp. 907-915 ◽  
Author(s):  
E.E. Rutherford ◽  
J.L. Ferguson ◽  
T.R. Geldart ◽  
G.M. Mead ◽  
J.M. Smart ◽  
...  
Keyword(s):  
Germ Cell ◽  
Late Relapse ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours
Sign in / Sign up

Export Citation Format

Share Document