Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation

2020 ◽  
Vol 63 (6) ◽  
pp. 3348-3358 ◽  
Author(s):  
John Liddle ◽  
Jonathan P. Hutchinson ◽  
Semra Kitchen ◽  
Paul Rowland ◽  
Margarete Neu ◽  
...  
Keyword(s):  
Antigen Presentation ◽  
Natural Product ◽  
Regulatory Site

Synthetic studies toward inducamide C

2021 ◽  
Author(s):  
Ardalan A. Nabi ◽  
Lydia M. Scott ◽  
Daniel P. Furkert ◽  
Jonathan Sperry
Keyword(s):  
Natural Product ◽  
Structural Revision ◽  
Synthetic Studies

The rare benzoxazepine ring in the alkaloid inducamide C is unstable and prone to rearrangement, indicating that structural revision of the natural product may be necessary.

Sign in / Sign up

Export Citation Format

Share Document