Discovery of Highly Potent Adenosine A1 Receptor Agonists: Targeting Positron Emission Tomography Probes

Adenosine A1 Receptor ◽

Emission Tomography ◽

Receptor Agonists ◽

Positron Emission ◽

Adenosine A1 ◽

Preclinical Evaluation of the First Adenosine A1 Receptor Partial Agonist Radioligand for Positron Emission Tomography Imaging

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b01009 ◽

2018 ◽

Vol 61 (22) ◽

pp. 9966-9975 ◽

Cited By ~ 11

Author(s):

Min Guo ◽

Zhan-Guo Gao ◽

Ryan Tyler ◽

Tyler Stodden ◽

Yang Li ◽

...

Keyword(s):

Partial Agonist ◽

Positron Emission Tomography Imaging ◽

Adenosine A1 Receptor ◽

Emission Tomography ◽

Tomography Imaging ◽

Preclinical Evaluation ◽

Positron Emission ◽

Adenosine A1 ◽

Increased Binding Potential of Brain Adenosine A1 Receptor in Chronic Stages of Patients with Diffuse Axonal Injury Measured with [1-methyl-11C] 8-dicyclopropylmethyl-1-methyl-3-propylxanthine Positron Emission Tomography Imaging

Journal of Neurotrauma ◽

10.1089/neu.2017.5006 ◽

2018 ◽

Vol 35 (1) ◽

pp. 25-31 ◽

Cited By ~ 5

Author(s):

Shihori Hayashi ◽

Motoki Inaji ◽

Tadashi Nariai ◽

Keiichi Oda ◽

Muneyuki Sakata ◽

...

Keyword(s):

Axonal Injury ◽

Diffuse Axonal Injury ◽

Positron Emission Tomography Imaging ◽

Emission Tomography ◽

Binding Potential ◽

Tomography Imaging ◽

Positron Emission ◽

Adenosine A1 ◽

Positron Emission Tomography to Elucidate Pharmacokinetic Differences of Regioisomeric Retinoid X Receptor Agonists

ACS Medicinal Chemistry Letters ◽

10.1021/ml500511m ◽

2015 ◽

Vol 6 (3) ◽

pp. 334-338 ◽

Cited By ~ 7

Author(s):

Toshiki Kobayashi ◽

Yuki Furusawa ◽

Shoya Yamada ◽

Masaru Akehi ◽

Fumiaki Takenaka ◽

...

Keyword(s):

Retinoid X Receptor ◽

Emission Tomography ◽

Receptor Agonists ◽

Positron Emission

Evaluation of adenosine A1 receptor agonists as neuroprotective countermeasures against Soman intoxication in rats

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2021.115466 ◽

2021 ◽

pp. 115466

Author(s):

Kristy L. Meads ◽

Thaddeus P. Thomas ◽

Jeffrey L. Langston ◽

Todd M. Myers ◽

Tsung-Ming Shih

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Agonists ◽

Adenosine A1 ◽

Time course of action of three adenosine A1 receptor agonists with differing lipophilicity in rats: comparison of pharmacokinetic, haemodynamic and EEG effects

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/pl00005124 ◽

1997 ◽

Vol 356 (6) ◽

pp. 827-837 ◽

Cited By ~ 6

Author(s):

E. A. van Schaick ◽

C. Kulkarni ◽

J. K. von Frijtag Drabbe Künzel ◽

R. A. A. Mathôt ◽

G. Cristalli ◽

...

Keyword(s):

Time Course ◽

Adenosine A1 Receptor ◽

Receptor Agonists ◽

Course Of Action ◽

Adenosine A1 ◽

Increase of waking and reduction of NREM and REM sleep after nitric oxide synthase inhibition: prevention with GABAA or adenosine A1 receptor agonists

Behavioural Brain Research ◽

10.1016/s0166-4328(01)00197-8 ◽

2001 ◽

Vol 123 (1) ◽

pp. 23-35 ◽

Cited By ~ 21

Author(s):

Jaime M. Monti ◽

Héctor Jantos ◽

Daniel Monti

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Rem Sleep ◽

Adenosine A1 Receptor ◽

Receptor Agonists ◽

Adenosine A1 ◽

A1 Receptor ◽

Oxide Synthase

The Effects of Intrathecal Adenosine A1 Receptor Agonists (R-PIA) on the Morphine Tolerance in a Rat Model of Postoperative Pain

Korean Journal of Anesthesiology ◽

10.4097/kjae.2007.52.2.212 ◽

2007 ◽

Vol 52 (2) ◽

pp. 212

Author(s):

In Gu Jun ◽

Long Zhe Piao ◽

Mi Young Kwon ◽

Jong Yeon Park

Keyword(s):

Postoperative Pain ◽

Rat Model ◽

Morphine Tolerance ◽

Adenosine A1 Receptor ◽

Receptor Agonists ◽

Adenosine A1 ◽

Pharmacokinetics and cardiovascular pharmaco-dynamics in rats of three adenosine A1-receptor agonists with differing lipophilicity

Pharmacological Research ◽

10.1016/1043-6618(95)86435-0 ◽

1995 ◽

Vol 31 ◽

pp. 44

Author(s):

E.A. van Schaick ◽

G. Cristalli ◽

A.P. Ijzerman ◽

M. Danhof

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Agonists ◽

Adenosine A1 ◽

Partial adenosine A1 receptor agonists for cardiovascular therapies

Purinergic Signalling ◽

10.1007/s11302-011-9274-3 ◽

2011 ◽

Vol 8 (S1) ◽

pp. 91-99 ◽

Cited By ~ 47

Author(s):

Barbara E. Albrecht-Küpper ◽

Kirsten Leineweber ◽

Peter G. Nell

Keyword(s):

Adenosine A1 Receptor ◽

Receptor Agonists ◽

Adenosine A1 ◽

Imaging of adenosine A1 receptors in the human brain by positron emission tomography with [11C]MPDX

Annals of Nuclear Medicine ◽

10.1007/bf03006445 ◽

2003 ◽

Vol 17 (6) ◽

pp. 511-515 ◽

Cited By ~ 26

Author(s):

Nobuyoshi Fukumitsu ◽

Kenji Ishii ◽

Yuichi Kimura ◽

Keiichi Oda ◽

Toru Sasaki ◽

...

Keyword(s):

Human Brain ◽

Emission Tomography ◽

Adenosine A1 Receptors ◽

Positron Emission ◽

Adenosine A1