scholarly journals Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls

2020 ◽  
Vol 22 (12) ◽  
pp. 833-843
Author(s):  
Olivier B. C. Monty ◽  
Nicholas Simmons ◽  
Srinivas Chamakuri ◽  
Martin M. Matzuk ◽  
Damian W. Young
Keyword(s):  
Peptide Synthesis ◽  
Solution Phase ◽  
Protecting Group ◽  
Reaction Conditions ◽  
Chemical Libraries

Cleavage of the Epimines of 1,6-Anhydrohexoses with Fluoride Anion

2005 ◽  
Vol 70 (12) ◽  
pp. 2075-2085 ◽  
Author(s):  
Jiří Kroutil ◽  
Klára Jeništová
Keyword(s):  
Fluoride Anion ◽  
Ring Cleavage ◽  
Protecting Group ◽  
Reaction Conditions ◽  
Aziridine Ring ◽  
Cleavage Reactions ◽  
Derivatives Of ◽  
Fluoro Derivatives

Aziridine ring cleavage reactions of five N-nosylepimines (2-6) having D-talo, D-galacto, D-manno, and D-allo configurations with potassium hydrogendifluoride under various reaction conditions have been performed. The cleavage regioselectively afforded diaxial isomers of vicinal amino-fluoro derivatives of 1,6-anhydro-β-D-gluco- and mannopyranose 7-11 in 51-94% yields. Removal of 2-nitrobenzenesulfonyl protecting group with benzenethiol has been attempted in the case of compound 10.

o-Nitrobenzoyl group as a new amino protecting group for peptide synthesis and the synthesis of some anthranilyl peptides

Tetrahedron ◽  
1973 ◽  
Vol 29 (4) ◽  
pp. 625-628 ◽  
Author(s):  
A.K. Koul ◽  
J.M. Bachhawat ◽  
B. Prashad ◽  
N.S. Ramegowda ◽  
A.K. Mathur ◽  
...  
Keyword(s):  
Peptide Synthesis ◽  
Protecting Group

The 2-chloro-3-indenylmethyloxycarbonyl and benz[f]inden-3-ylmethyloxycarbonyl base-sensitive amino-protecting group. Application to an inverse Merrifield approach to peptide synthesis

1990 ◽  
Vol 55 (1) ◽  
pp. 251-259 ◽  
Author(s):  
Louis A. Carpino ◽  
Beri J. Cohen ◽  
Yao Zhong Lin ◽  
Kenton E. Stephens ◽  
Salvatore A. Triolo
Keyword(s):  
Peptide Synthesis ◽  
Protecting Group

scholarly journals Application of an Automated Synthesis Suite to Parallel Solution-Phase Peptide Synthesis.

2001 ◽  
Vol 49 (9) ◽  
pp. 1147-1154 ◽  
Author(s):  
Noritaka KURODA ◽  
Taeko HATTORI ◽  
Yoko FUJIOKA ◽  
David G. CORK ◽  
Chieko KITADA ◽  
...  
Keyword(s):  
Peptide Synthesis ◽  
Solution Phase ◽  
Automated Synthesis ◽  
Parallel Solution

ChemInform Abstract: New Strategies for an Efficient Removal of the 9-Fluorenylmethoxycarbonyl (Fmoc) Protecting Group in the Peptide Synthesis.

ChemInform ◽  
2010 ◽  
Vol 31 (16) ◽  
pp. no-no
Author(s):  
Antonella Leggio ◽  
Angelo Liguori ◽  
Anna Napoli ◽  
Carlo Siciliano ◽  
Giovanni Sindona
Keyword(s):  
Peptide Synthesis ◽  
Protecting Group ◽  
Efficient Removal ◽  
Fmoc Protecting Group ◽  
New Strategies
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