Active site specific cadmium(II)-substituted horse liver alcohol dehydrogenase: crystal structures of the free enzyme, its binary complex with NADH, and the ternary complex with NADH and bound p-bromobenzyl alcohol

Site Specific ◽

Active-Site-Specific Reconstituted Cobalt(II) Horse-Liver Alcohol Dehydrogenase. Changes of the Spectra of the Substrate trans-4-(N,N-Dimethylamino)-cinnamaldehyde and of the Catalytic Cobalt Ion upon Ternary Complex Formation with NADH and 1,4,5,6-Tetrahydronkotinamide-Adenine Dinucleotide

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1979.tb02057.x ◽

1979 ◽

Vol 100 (1) ◽

pp. 267-270 ◽

Cited By ~ 28

Author(s):

Helmut DIETRICH ◽

Wolfgang MARET ◽

Leif WALLEN ◽

Michael ZEPPEZAUER

Keyword(s):

Complex Formation ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Ternary Complex ◽

Site Specific ◽

Cobalt Ion ◽

Ternary Complex Formation ◽

Crystal structures of the active site in specifically metal-depleted and cobalt-substituted horse liver alcohol dehydrogenase derivatives.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.80.17.5289 ◽

1983 ◽

Vol 80 (17) ◽

pp. 5289-5293 ◽

Cited By ~ 28

Author(s):

G. Schneider ◽

H. Eklund ◽

E. Cedergren-Zeppezauer ◽

M. Zeppezauer

Keyword(s):

Alcohol Dehydrogenase ◽

Crystal Structures ◽

Active Site ◽

Active site-specific reconstituted copper(II) horse liver alcohol dehydrogenase: A biological model for type 1 Cu2+ and its changes upon ligand binding and conformational transitions

Journal of Inorganic Biochemistry ◽

10.1016/s0162-0134(00)80205-6 ◽

1980 ◽

Vol 12 (3) ◽

pp. 241-252 ◽

Cited By ~ 43

Author(s):

Wolfgang Maret ◽

Helmut Dietrich ◽

Hans-Heinrich Ruf ◽

Michael Zeppezauer

Keyword(s):

Alcohol Dehydrogenase ◽

Ligand Binding ◽

Active Site ◽

Conformational Transitions ◽

Biological Model ◽

Site Specific ◽

Chloroprothixene binding into the active site pocket of horse liver alcohol dehydrogenase

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19760928 ◽

1976 ◽

Vol 41 (3) ◽

pp. 928-940 ◽

Cited By ~ 1

Author(s):

J. Kovář ◽

L. Skurský ◽

K. Bláha

Keyword(s):

Alcohol Dehydrogenase ◽

Active Site ◽

Active Site Pocket ◽

Binding of substrate in a ternary complex of horse liver alcohol dehydrogenase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)45387-8 ◽

1982 ◽

Vol 257 (23) ◽

pp. 14349-14358 ◽

Cited By ~ 1

Author(s):

H Eklund ◽

B V Plapp ◽

J P Samama ◽

C I Brändén

Keyword(s):

Alcohol Dehydrogenase ◽

Ternary Complex ◽

Covalent binding of an NAD+ analogue to horse liver alcohol dehydrogenase in a ternary complex with pyrazole

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1987.tb13440.x ◽

1987 ◽

Vol 168 (2) ◽

pp. 469-473 ◽

Cited By ~ 10

Author(s):

Philippe GOULAS

Keyword(s):

Alcohol Dehydrogenase ◽

Ternary Complex ◽

Covalent Binding ◽

Response to Comment on “Effect of Active Site Mutation Phe93 → Trp in the Horse Liver Alcohol Dehydrogenase Enzyme on Catalysis: A Molecular Dynamics Study”

The Journal of Physical Chemistry B ◽

10.1021/jp035474+ ◽

2003 ◽

Vol 107 (44) ◽

pp. 12372-12372 ◽

Cited By ~ 2

Author(s):

Steven D. Schwartz

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Site Mutation ◽

Horse Liver ◽

Dehydrogenase Enzyme

Active-site cobalt(II)-substituted horse liver alcohol dehydrogenase: characterization of intermediates in the oxidation and reduction processes as a function of pH

Biochemistry ◽

10.1021/bi00377a031 ◽

1987 ◽

Vol 26 (3) ◽

pp. 871-882 ◽

Cited By ~ 31

Author(s):

Christian Sartorius ◽

Martin Gerber ◽

Michael Zeppezauer ◽

Michael F. Dunn

Keyword(s):

Alcohol Dehydrogenase ◽

Active Site ◽

Reduction Processes ◽

Comment on “Effect of Active Site Mutation Phe93 → Trp in the Horse Liver Alcohol Dehydrogenase Enzyme on Catalysis: A Molecular Dynamics Study”

The Journal of Physical Chemistry B ◽

10.1021/jp034932b ◽

2003 ◽

Vol 107 (44) ◽

pp. 12370-12371 ◽

Cited By ~ 10

Author(s):

Arieh Warshel ◽

Jordi Villà-Freixa

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Site Mutation ◽

Horse Liver ◽

Dehydrogenase Enzyme

Determination of the pKa for histidine-51 residue in the ternary complex of horse liver alcohol dehydrogenase

Archives of Pharmacal Research ◽

10.1007/bf02974060 ◽

1992 ◽

Vol 15 (3) ◽

pp. 229-233 ◽

Cited By ~ 1

Author(s):

Kang Man Lee ◽

Su Yeon Son

Keyword(s):

Alcohol Dehydrogenase ◽

Ternary Complex ◽