Threonine inhibition of the aspartokinase-homoserine dehydrogenase I of Escherichia coli. A slow transient and cooperativity of inhibition of the aspartokinase activity

Biochemistry ◽

10.1021/bi00610a016 ◽

1978 ◽

Vol 17 (17) ◽

pp. 3523-3530 ◽

Author(s):

Cynthia F. Bearer ◽

Kenneth E. Neet

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase

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The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Carboxymethylation of the enzyme: threonine binding and inhibition are functionally dissociable.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)40886-6 ◽

1978 ◽

Vol 253 (8) ◽

pp. 2754-2757 ◽

Author(s):

E. Fontan ◽

P. Truffa-Bachi

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase ◽

Escherichia Coli K12

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Aspartokinase I-homoserine dehydrogenase I of Escherichia coli K12. Concentration-dependent dissociation to dimers in the presence of L-threonine.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)38053-5 ◽

1978 ◽

Vol 253 (7) ◽

pp. 2155-2160 ◽

Author(s):

L.P. Vickers ◽

G.K. Ackers ◽

J.W. Ogilvie

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase ◽

Escherichia Coli K12

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The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Carboxymethylation of a unique cysteine induces a conformational change of the enzyme.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)40887-8 ◽

1978 ◽

Vol 253 (8) ◽

pp. 2758-2762

Author(s):

E. Fontan ◽

P. Truffa-Bachi

Keyword(s):

Escherichia Coli ◽

Conformational Change ◽

Homoserine Dehydrogenase ◽

Escherichia Coli K12

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A hybrid proteolytic fragment of Escherichia coli aspartokinase I-homoserine dehydrogenase I. Structure, inhibition pattern, dissociation properties, and generation of two homodimers.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)43952-4 ◽

1983 ◽

Vol 258 (22) ◽

pp. 13570-13574

Author(s):

A Fazel ◽

Y Guillou ◽

G N Cohen

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase ◽

Proteolytic Fragment ◽

Inhibition Pattern

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Kinetic and regulatory mechanisms for (Escherichia coli) homoserine dehydrogenase-I. Equilibrium isotope exchange kinetics.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)53478-5 ◽

1993 ◽

Vol 268 (7) ◽

pp. 4880-4888

Author(s):

F.C. Wedler ◽

B.W. Ley

Keyword(s):

Escherichia Coli ◽

Isotope Exchange ◽

Regulatory Mechanisms ◽

Homoserine Dehydrogenase ◽

Exchange Kinetics ◽

Isotope Exchange Kinetics

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The interaction between Escherichia coli aspartokinase-homoserine dehydrogenase and 3-acetylpyridine-adenine dinucleotide phosphate (reduced), an analog of NADPH.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)43345-x ◽

1984 ◽

Vol 259 (4) ◽

pp. 2252-2256

Author(s):

K Müller ◽

J R Garel

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase

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The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli

Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation ◽

10.1016/0926-6593(66)90004-x ◽

1966 ◽

Vol 128 (3) ◽

pp. 440-449 ◽

Author(s):

Paolo Truffa-Bachi ◽

Gérard Le Bras ◽

Georges N. Cohen

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase

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The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli

Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation ◽

10.1016/0926-6593(66)90005-1 ◽

1966 ◽

Vol 128 (3) ◽

pp. 450-453 ◽

Author(s):

Paolo Truffa-Bachi ◽

Gisèle Le Bras ◽

Georges N. Cohen

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase

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Threonine-sensitive aspartokinase-homoserine dehydrogenase of Escherichia coli K 12. Reaction with 6-mercapto-9-β-D-ribofuranosylpurine 5'-triphosphate

Biochemistry ◽

10.1021/bi00790a007 ◽

1971 ◽

Vol 10 (14) ◽

pp. 2700-2706 ◽

Author(s):

Henry D'A. Heck ◽

Paolo Truffa-Bachi

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase ◽

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Revised Structure of Aspartokinase I-Homoserine Dehydrogenase I of Escherichia coli K12. Evidence for Four Identical Subunits

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1972.tb01938.x ◽

1972 ◽

Vol 28 (4) ◽

pp. 507-519 ◽

Author(s):

Francoise Falcoz-Kelly ◽

Joel Janin ◽

John C. Saari ◽

Michel Veron ◽

Paolo Truffa-Bachi ◽

...

Keyword(s):

Escherichia Coli ◽

Homoserine Dehydrogenase ◽

Escherichia Coli K12

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