scholarly journals Non-canonical 3′-5′ Extension of RNA with Prebiotically Plausible Ribonucleoside 2′,3′-Cyclic Phosphates

2014 ◽  
Vol 136 (14) ◽  
pp. 5193-5196 ◽  
Author(s):  
Hannes Mutschler ◽  
Philipp Holliger
Keyword(s):  
Cyclic Phosphates

A novel compound active against SARS-CoV-2 targeting Uridylate-specific endoribonuclease (NendoU/NSP15): In silico and in vitro investigations

2021 ◽  
Author(s):  
Sumit Kumar ◽  
Yash Gupta ◽  
Samantha Zak ◽  
Charu Upadhyay ◽  
Neha Sharma ◽  
...  
Keyword(s):  
Virtual Screening ◽  
High Throughput ◽  
In Silico ◽  
Specific Enzyme ◽  
Cyclic Phosphates ◽  
High Throughput Virtual Screening

NendoU (NSP15) is an Mn(2+)-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond. Our in-house library was subjected to high throughput virtual screening (HTVS) to identify compounds...

scholarly journals Phospholipase D Toxins of Brown Spider Venom Convert Lysophosphatidylcholine and Sphingomyelin to Cyclic Phosphates

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e72372 ◽  
Author(s):  
Daniel M. Lajoie ◽  
Pamela A. Zobel-Thropp ◽  
Vlad K. Kumirov ◽  
Vahe Bandarian ◽  
Greta J. Binford ◽  
...  
Keyword(s):  
Phospholipase D ◽  
Spider Venom ◽  
Brown Spider ◽  
Cyclic Phosphates

New aspects of formation of 1,2-cyclic phosphates by phospholipase C-δ1

2003 ◽  
Vol 11 (11) ◽  
pp. 2471-2475 ◽  
Author(s):  
Yinghui Liu ◽  
Karol S Bruzik ◽  
Bharath Ananthanarayanan ◽  
Wonhwa Cho
Keyword(s):  
Phospholipase C ◽  
Cyclic Phosphates

Isolation of pentacoordinate species during reactions of five-membered cyclic phosphates an —evidence for pentacoordinate intermediates—

1974 ◽  
Vol 15 (12) ◽  
pp. 1075-1078 ◽  
Author(s):  
Toru Koizumi ◽  
Yutaka Watanabe ◽  
Yuichi Yoshida ◽  
Eiichi Yoshii
Keyword(s):  
Cyclic Phosphates
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