Synthesis and Structure−Activity Relationships of a New Set of 2-Arylpyrazolo[3,4-c]quinoline Derivatives as Adenosine Receptor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm000936i ◽

2000 ◽

Vol 43 (16) ◽

pp. 3118-3124 ◽

Author(s):

Vittoria Colotta ◽

Daniela Catarzi ◽

Flavia Varano ◽

Lucia Cecchi ◽

Guido Filacchioni ◽

...

Keyword(s):

Adenosine Receptor ◽

Quinoline Derivatives ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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ChemInform Abstract: New Nonpeptide Angiotensin II Receptor Antagonists. Part 2. Synthesis, Biological Properties, and Structure-Activity Relationships of 2-Alkyl- 4-(biphenylylmethoxy)quinoline Derivatives.

10.1002/chin.199321171 ◽

2010 ◽

Vol 24 (21) ◽

pp. no-no

Author(s):

R. H. BRADBURY ◽

C. P. ALLOTT ◽

M. DENNIS ◽

E. FISHER ◽

J. S. MAJOR ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Properties ◽

Quinoline Derivatives ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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Synthesis and Structure-Activity Relationships of 4-Cycloalkylamino-1, 2, 4-triazolo[4, 3-a]quinoxalin-1- one Derivatives as A1 and A3 Adenosine Receptor Antagonists

Archiv der Pharmazie ◽

10.1002/ardp.200300816 ◽

2004 ◽

Vol 337 (1) ◽

pp. 35-41 ◽

Author(s):

Vittoria Colotta ◽

Daniela Catarzi ◽

Flavia Varano ◽

Guido Filacchioni ◽

Claudia Martini ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity ◽

A3 Adenosine Receptor

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Structure–Activity Relationships and Molecular Modeling of 1,2,4-Triazoles as Adenosine Receptor Antagonists

ACS Medicinal Chemistry Letters ◽

10.1021/ml300097g ◽

2012 ◽

Vol 3 (9) ◽

pp. 715-720 ◽

Author(s):

Jens Carlsson ◽

Dilip K. Tosh ◽

Khai Phan ◽

Zhan-Guo Gao ◽

Kenneth A. Jacobson

Keyword(s):

Molecular Modeling ◽

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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Chiral Pyrrolo[2,3-d]pyrimidine and Pyrimido[4,5-b]indole Derivatives: Structure−Activity Relationships of Potent, Highly Stereoselective A1-Adenosine Receptor Antagonists†,‡

Journal of Medicinal Chemistry ◽

10.1021/jm960011w ◽

1996 ◽

Vol 39 (13) ◽

pp. 2482-2491 ◽

Author(s):

Christa E. Müller ◽

Uli Geis ◽

Bettina Grahner ◽

Wolfgang Lanzner ◽

Kurt Eger

Keyword(s):

Adenosine Receptor ◽

Indole Derivatives ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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Structure–activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.03.034 ◽

2009 ◽

Vol 17 (10) ◽

pp. 3733-3738 ◽

Author(s):

Shantanu Pal ◽

Won Jun Choi ◽

Seung Ah Choe ◽

Cara L. Heller ◽

Zhan-Guo Gao ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity ◽

A3 Adenosine Receptor ◽

Adenosine Derivatives

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New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)quinoline derivatives

Journal of Medicinal Chemistry ◽

10.1021/jm00100a007 ◽

1992 ◽

Vol 35 (22) ◽

pp. 4027-4038 ◽

Author(s):

Robert H. Bradbury ◽

Christopher P. Allott ◽

Michael Dennis ◽

Eric Fisher ◽

John S. Major ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Properties ◽

Quinoline Derivatives ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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2-Amino[1,2,4]triazolo[1,5-c]quinazolines and Derived Novel Heterocycles: Syntheses and Structure-Activity Relationships of Potent Adenosine Receptor Antagonists

ChemMedChem ◽

10.1002/cmdc.201600255 ◽

2016 ◽

Vol 11 (20) ◽

pp. 2272-2286 ◽

Author(s):

Joachim C. Burbiel ◽

Wadih Ghattas ◽

Petra Küppers ◽

Meryem Köse ◽

Svenja Lacher ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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Synthesis and Structure−Activity Relationships of 3,7-Dimethyl-1-propargylxanthine Derivatives, A2A-Selective Adenosine Receptor Antagonists†

Journal of Medicinal Chemistry ◽

10.1021/jm970515+ ◽

1997 ◽

Vol 40 (26) ◽

pp. 4396-4405 ◽

Author(s):

Christa E. Müller ◽

Uli Geis ◽

Jo Hipp ◽

Ulrike Schobert ◽

Wolfram Frobenius ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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Structure–activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(00)00271-6 ◽

2001 ◽

Vol 9 (3) ◽

pp. 575-583 ◽

Author(s):

Giovannella Strappaghetti ◽

Stefano Corsano ◽

Roberta Barbaro ◽

Gino Giannaccini ◽

Laura Betti

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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Synthesis and structure–Activity relationships of a new set of 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as adenosine receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(03)00338-9 ◽

2003 ◽

Vol 11 (16) ◽

pp. 3541-3550 ◽

Author(s):

V Colotta

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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