Optimal Recognition of Neutral Endopeptidase and Angiotensin-Converting Enzyme Active Sites by Mercaptoacyldipeptides as a Means To Design Potent Dual Inhibitors

1996 ◽  
Vol 39 (6) ◽  
pp. 1210-1219 ◽  
Author(s):  
Pascale Coric ◽  
Serge Turcaud ◽  
Hervé Meudal ◽  
Bernard Pierre Roques ◽  
Marie-Claude Fournie-Zaluski
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Active Sites ◽  
Neutral Endopeptidase ◽  
Converting Enzyme ◽  
Enzyme Active Sites ◽  
Dual Inhibitors

Mercaptoacyl Dipeptides as Orally Active Dual Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase

1996 ◽  
Vol 39 (16) ◽  
pp. 3158-3168 ◽  
Author(s):  
Cynthia A. Fink ◽  
J. Eric Carlson ◽  
Patricia A. McTaggart ◽  
Ying Qiao ◽  
Randy Webb ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Neutral Endopeptidase ◽  
Converting Enzyme ◽  
Dual Inhibitors ◽  
Orally Active

Design of Orally Active Dual Inhibitors of Neutral Endopeptidase and Angiotensin-Converting Enzyme with Long Duration of Action

1996 ◽  
Vol 39 (13) ◽  
pp. 2594-2608 ◽  
Author(s):  
Marie-Claude Fournie-Zaluski ◽  
Pascale Coric ◽  
Vincent Thery ◽  
Walter Gonzalez ◽  
Hervé Meudal ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Neutral Endopeptidase ◽  
Converting Enzyme ◽  
Duration Of Action ◽  
Long Duration ◽  
Dual Inhibitors ◽  
Orally Active

New enkephalinase inhibitors as probes to differentiate “enkephalinase” and angiotensin-converting-enzyme active sites

Life Sciences ◽  
1982 ◽  
Vol 31 (16-17) ◽  
pp. 1749-1752 ◽  
Author(s):  
B.P. Roques ◽  
M.C. Fournié-Zaluski ◽  
D. Florentin ◽  
G. Waksman ◽  
A. Sassi ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Active Sites ◽  
Converting Enzyme ◽  
Enzyme Active Sites ◽  
Enkephalinase Inhibitors
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