Enantiomeric excess determination without chiral auxiliary compounds. A new phosphorus-31 NMR method for amino acid esters and primary amines

1986 ◽  
Vol 51 (26) ◽  
pp. 5484-5486 ◽  
Author(s):  
Ben L. Feringa ◽  
Bert Strijtveen ◽  
Richard M. Kellogg
Keyword(s):  
Amino Acid ◽  
Enantiomeric Excess ◽  
Chiral Auxiliary ◽  
Primary Amines ◽  
Amino Acid Esters ◽  
Nmr Method ◽  
Acid Esters

ChemInform Abstract: A New 31P NMR Method for the Enantiomeric Excess Determination of Alcohols, Amines, and Amino Acid Esters.

ChemInform ◽  
2010 ◽  
Vol 24 (28) ◽  
pp. no-no
Author(s):  
R. HULST ◽  
R. W. J. ZIJLSTRA ◽  
B. L. FERINGA ◽  
N. KOEN DE VRIES ◽  
W. TEN HOEVE ◽  
...  
Keyword(s):  
Amino Acid ◽  
31P Nmr ◽  
Enantiomeric Excess ◽  
Amino Acid Esters ◽  
Nmr Method ◽  
Acid Esters

A new 31P NMR method for the enantiomeric excess determination of alcohols, amines and amino acid esters

1993 ◽  
Vol 34 (8) ◽  
pp. 1339-1342 ◽  
Author(s):  
Ron Hulst ◽  
Robert W.J. Zijlstra ◽  
Ben L. Feringa ◽  
N.Koen de Vries ◽  
Wolter ten Hoeve ◽  
...  
Keyword(s):  
Amino Acid ◽  
31P Nmr ◽  
Enantiomeric Excess ◽  
Amino Acid Esters ◽  
Nmr Method ◽  
Acid Esters

scholarly journals Synthesis of novel pregnane-based 20-carboxamides via palladium-catalysed aminocarbonylation

2021 ◽  
Author(s):  
Gábor Mikle ◽  
Alexandra Zugó ◽  
Erzsébet Szatnik ◽  
Anita Maxim ◽  
Sándor Mahó ◽  
...  
Keyword(s):  
Amino Acid ◽  
Selective Hydrogenation ◽  
Primary Amines ◽  
Amino Acid Esters ◽  
Acid Esters

Abstract20-Carboxamidopregnene derivatives, such as 3β-acetoxy-5α-pregn-20-ene-20-carboxamides and 5α-pregn-20-ene-20-carboxamides were synthesized from the widely accessible 3β-acetoxy-pregn-5,16-dien-20-one (PDA) using selective hydrogenation, hydrazine and iodoalkene formation, as well as palladium-catalysed aminocarbonylation. The 20-iodo-20-ene derivatives, obtained from the corresponding 20-keto derivatives via their hydrazones, served as substrates. 23 new 20-carboxamides were obtained using various N-nucleophiles ranging from simple primary amines to α-amino acid esters. The novelty of this methodology lies in the application of facile, moderate or high-yielding reactions to obtain otherwise hardly accessible steroidal 20-carboxamides of pharmaceutical importance. In other words, instead of the enzymatic or synthetic degradation of e.g., sterols or cholanic acids, functionalization of the basic skeleton (a ‘building-up’ approach) was used.

ChemInform Abstract: Amino Acid Esters as Chiral Auxiliary Groups

ChemInform ◽  
2010 ◽  
Vol 23 (3) ◽  
pp. no-no
Author(s):  
H. WALDMANN
Keyword(s):  
Amino Acid ◽  
Chiral Auxiliary ◽  
Amino Acid Esters ◽  
Acid Esters

ChemInform Abstract: A Remarkably Simple Protocol for the N-Formylation of Amino Acid Esters and Primary Amines.

ChemInform ◽  
2011 ◽  
Vol 42 (50) ◽  
pp. no-no
Author(s):  
Mojmir Suchy ◽  
Adam A. H. Elmehriki ◽  
Robert H. E. Hudson
Keyword(s):  
Amino Acid ◽  
Primary Amines ◽  
Amino Acid Esters ◽  
Simple Protocol ◽  
Acid Esters
Sign in / Sign up

Export Citation Format

Share Document