Development and Characterization of a Scalable Controlled Precipitation Process to Enhance the Dissolution of Poorly Water-Soluble Drugs

Pharmaceutical Research ◽

10.1023/b:pham.0000048196.61887.e5 ◽

2004 ◽

Vol 21 (11) ◽

pp. 2048-2057 ◽

Author(s):

True L. Rogers ◽

Ian B. Gillespie ◽

James E. Hitt ◽

Kevin L. Fransen ◽

Cindy A. Crowl ◽

...

Keyword(s):

Water Soluble ◽

Precipitation Process ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble ◽

Controlled Precipitation

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Characterization of a quaternary liquid system improving the bioavailability of poorly water soluble drugs

Journal of Colloid and Interface Science ◽

10.1016/s0021-9797(03)00321-7 ◽

2003 ◽

Vol 263 (2) ◽

pp. 590-596 ◽

Author(s):

F. Meriani ◽

N. Coceani ◽

C. Sirotti ◽

D. Voinovich ◽

M. Grassi

Keyword(s):

Liquid System ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Particle Characterization of Poorly Water-Soluble Drugs Using a Spray Freeze Drying Technique

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.57.657 ◽

2009 ◽

Vol 57 (7) ◽

pp. 657-662 ◽

Author(s):

Masahiro Kondo ◽

Toshiyuki Niwa ◽

Hirokazu Okamoto ◽

Kazumi Danjo

Keyword(s):

Freeze Drying ◽

Water Soluble ◽

Particle Characterization ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Spray Freeze Drying ◽

Poorly Water Soluble

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Particle Engineering of Poorly Water Soluble Drugs by Controlled Precipitation

ACS Symposium Series - Polymeric Drug Delivery II ◽

10.1021/bk-2006-0924.ch019 ◽

2006 ◽

pp. 292-304 ◽

Author(s):

E. J. Elder ◽

J. E. Hitt ◽

T. L. Rogers ◽

C. J. Tucker ◽

S. Saghir ◽

...

Keyword(s):

Water Soluble ◽

Particle Engineering ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble ◽

Controlled Precipitation

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Characterization of the Precipitates of Poorly Water Soluble Drugs and Determination of the Solubilities in Human Gastro-Intestinal Fluids by Microsopy

Drug Development and Industrial Pharmacy ◽

10.3109/03639049309063005 ◽

1993 ◽

Vol 19 (10) ◽

pp. 1103-1112 ◽

Author(s):

D. M. Simmons

Keyword(s):

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Intestinal Fluids ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Development and Characterization of a Biocompatible Soybean Oil-Based Microemulsion for the Delivery of Poorly Water-Soluble Drugs

Journal of Pharmaceutical Sciences ◽

10.1002/jps.24555 ◽

2015 ◽

Vol 104 (10) ◽

pp. 3535-3543 ◽

Author(s):

Carolina Aloisio ◽

Marcela R. Longhi ◽

Anselmo Gomes De Oliveira

Keyword(s):

Soybean Oil ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers

Journal of Pharmacy and Pharmacology ◽

10.1211/0022357011775532 ◽

2001 ◽

Vol 53 (3) ◽

pp. 303-315 ◽

Author(s):

Angus Forster ◽

John Hempenstall ◽

Thomas Rades

Keyword(s):

Amorphous Polymers ◽

Water Soluble ◽

Melt Extrusion ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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In Vitro and In Vivo Characterization of Drug Nanoparticles Prepared Using PureNano™ Continuous Crystallizer to Improve the Bioavailability of Poorly Water Soluble Drugs

Pharmaceutical Research ◽

10.1007/s11095-016-1964-7 ◽

2016 ◽

Vol 33 (9) ◽

pp. 2259-2268 ◽

Author(s):

Kohei Tahara ◽

Masahiro Nishikawa ◽

Ko Matsui ◽

Koji Hisazumi ◽

Risako Onodera ◽

...

Keyword(s):

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Drug Nanoparticles ◽

Water Soluble Drugs ◽

Poorly Water Soluble ◽

In Vivo Characterization

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Characterization of Self-Emulsifying Drug Delivery Systems Using In Situ Raman Spectroscopy to Study the Precipitation Inhibition Mechanism of Poorly Water-Soluble Drugs

Journal of Pharmaceutical Innovation ◽

10.1007/s12247-018-9315-3 ◽

2018 ◽

Vol 13 (2) ◽

pp. 144-154

Author(s):

Shilpa Raut ◽

Eman Atef

Keyword(s):

Water Soluble ◽

Inhibition Mechanism ◽

In Situ Raman Spectroscopy ◽

Poorly Water Soluble Drugs ◽

Precipitation Inhibition ◽

In Situ Raman ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Dissolution and Solid-State Characterization of Poorly Water-Soluble Drugs in the Presence of a Hydrophilic Carrier

AAPS PharmSciTech ◽

10.1208/s12249-011-9697-8 ◽

2011 ◽

Vol 12 (4) ◽

pp. 1227-1233 ◽

Author(s):

Rahmat Talukder ◽

Chase Reed ◽

Thomas Dürig ◽

Muhammad Hussain

Keyword(s):

Solid State ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble ◽

Solid State Characterization

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Separation and Characterization of the Colloidal Phases Produced on Digestion of Common Formulation Lipids and Assessment of Their Impact on the Apparent Solubility of Selected Poorly Water-Soluble Drugs

Journal of Pharmaceutical Sciences ◽

10.1002/jps.10329 ◽

2003 ◽

Vol 92 (3) ◽

pp. 634-648 ◽

Author(s):

Greg A. Kossena ◽

Ben J. Boyd ◽

Christopher J.H. Porter ◽

William N. Charman

Keyword(s):

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Apparent Solubility ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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