scholarly journals Chlorate toxicity in Aspergillus nidulans: The selection and characterisation of chlorate resistant mutants

Heredity ◽  
1976 ◽  
Vol 36 (2) ◽  
pp. 191-203 ◽  
Author(s):  
D J Cove
1979 ◽  
Vol 34 (1) ◽  
pp. 19-32 ◽  
Author(s):  
A. Brian Tomsett ◽  
David J. Cove

SUMMARYThe genetic fine-structure of theniiAniaD gene region ofAspergillus nidulanshas been studied using deletion mapping. Deletions were identified asniiAniaD double mutants and comprised 1% of spontaneous chlorate-resistant mutants. All such double mutants were shown to involve deletions and their frequency was not increased by mutagenic treatment with eitherN-methyl-N′-nitro-N-nitrosoguanidine or with ultraviolet light. Deletion maps of theniaD andniiA genes have been constructed. A further class of mutation was also mapped using the deletions. Thesecrnmutations, which affect a gene whose function is as yet unknown, map on the centromere proximal side ofniiA. This analysis of a eukaryote gene cluster will provide a framework upon which to base studies of the regulation of the nitrate assimilation pathway.


1989 ◽  
Vol 220 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Masaaki Takahashi ◽  
Msayoshi Kobayashi ◽  
Shigeo Iwasaki

1971 ◽  
Vol 111 (2) ◽  
pp. 185-193 ◽  
Author(s):  
M. Victoria Elorza ◽  
Herbert N. Arst

Sign in / Sign up

Export Citation Format

Share Document