Sunitinib, an orally available receptor tyrosine kinase inhibitor, induces monocytic differentiation of acute myelogenous leukemia cells that is enhanced by 1,25-dihydroxyvitamin D3

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Monocytic Differentiation ◽

Dihydroxyvitamin D3 ◽

Multitargeted tyrosine kinase inhibitor stimulates expression of IL-6 and activates JAK2/STAT5 signaling in acute myelogenous leukemia cells

Leukemia ◽

10.1038/leu.2009.163 ◽

2009 ◽

Vol 23 (12) ◽

pp. 2304-2308 ◽

Cited By ~ 8

Author(s):

C Nishioka ◽

T Ikezoe ◽

J Yang ◽

A Yokoyama

Keyword(s):

Tyrosine Kinase ◽

Multitargeted Tyrosine Kinase Inhibitor

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Acute Myelogenous ◽

156 ANALYSIS OF A TARGETED RECEPTOR TYROSINE KINASE INHIBITOR IN THE TREATMENT OF ACUTE MYELOGENOUS LEUKEMIA

Journal of Investigative Medicine ◽

10.2310/6650.2005.00005.155 ◽

2005 ◽

Vol 53 (1) ◽

pp. S105.1-S105

Author(s):

L. P. Menzel ◽

D. B. Shankar ◽

N. P. Shah ◽

R. Hummerickhouse ◽

A. Hagey ◽

...

Keyword(s):

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Receptor Tyrosine Kinase Inhibitor ◽

VX-322: A Novel Dual Receptor Tyrosine Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia

Journal of Medicinal Chemistry ◽

10.1021/jm201198w ◽

2012 ◽

Vol 55 (2) ◽

pp. 725-734 ◽

Cited By ~ 11

Author(s):

David K. Heidary ◽

George Huang ◽

Diane Boucher ◽

Jianguo Ma ◽

Cornelia Forster ◽

...

Keyword(s):

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Receptor Tyrosine Kinase Inhibitor ◽

Targeting PFKFB3 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitor

Oncogene ◽

10.1038/s41388-018-0157-8 ◽

2018 ◽

Vol 37 (21) ◽

pp. 2837-2849 ◽

Cited By ~ 10

Author(s):

Yu Zhu ◽

Luo Lu ◽

Chun Qiao ◽

Yi Shan ◽

Huapeng Li ◽

...

Keyword(s):

Tyrosine Kinase ◽

Chronic Myelogenous Leukemia Cells

Chronic Myelogenous Leukemia ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Abstract 158: Cyclopamine, an inhibitor of hedgehog signaling, induces monocytic differentiation of acute myelogenous leukemia cells

10.1158/1538-7445.am2012-158 ◽

2012 ◽

Author(s):

Li-Yuan Bai ◽

Jing-Ru Weng ◽

Chang-Fang Chiu ◽

Wen-Jyi Lo ◽

Cheng-Wen Lin

Keyword(s):

Hedgehog Signaling ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Monocytic Differentiation ◽

The FLT3 Internal Tandem Duplication Mutation Is a Secondary Target of the Aurora B Kinase Inhibitor AZD1152-HQPA in Acute Myelogenous Leukemia Cells

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-09-1144 ◽

2010 ◽

Vol 9 (3) ◽

pp. 661-672 ◽

Cited By ~ 29

Author(s):

Martin Grundy ◽

Claire Seedhouse ◽

Shilli Shang ◽

Jaineeta Richardson ◽

Nigel Russell ◽

...

Keyword(s):

Tandem Duplication ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Aurora B ◽

Internal Tandem Duplication ◽

Secondary Target ◽

Acute Myelogenous ◽

Flt3 Internal Tandem Duplication

Faculty Opinions recommendation of Targeting PFKFB3 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732811511.793583303 ◽

2021 ◽

Author(s):

Daniela Krause

Keyword(s):

Tyrosine Kinase ◽

Chronic Myelogenous Leukemia Cells

Chronic Myelogenous Leukemia ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

SAHA and S116836, a novel tyrosine kinase inhibitor, synergistically induce apoptosis in imatinib-resistant chronic myelogenous leukemia cells

Cancer Biology & Therapy ◽

10.4161/cbt.28931 ◽

2014 ◽

Vol 15 (7) ◽

pp. 951-962 ◽

Cited By ~ 13

Author(s):

Qiangui Bu ◽

Lijing Cui ◽

Juan Li ◽

Xin Du ◽

Waiyi Zou ◽

...

Keyword(s):

Tyrosine Kinase ◽

Chronic Myelogenous Leukemia Cells

Chronic Myelogenous Leukemia ◽

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Imatinib Resistant ◽

Abstract 2502: p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells

10.1158/1538-7445.am10-2502 ◽

2010 ◽

Author(s):

Takayuki Ikezoe ◽

Jing Yang ◽

Chie Nishioka ◽

Akihito Yokoyama

Keyword(s):

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Aurora B ◽

Aurora B Kinase ◽

p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells

International Journal of Hematology ◽

10.1007/s12185-009-0462-7 ◽

2009 ◽

Vol 91 (1) ◽

pp. 69-77 ◽

Cited By ~ 20

Author(s):

Takayuki Ikezoe ◽

Jing Yang ◽

Chie Nishioka ◽

Akihito Yokoyama

Keyword(s):

Kinase Inhibitor ◽

Myelogenous Leukemia ◽

Leukemia Cells ◽

Aurora B ◽

Aurora B Kinase ◽