Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial

Nature Medicine ◽

10.1038/s41591-021-01600-6 ◽

2022 ◽

Author(s):

Thomas Powles ◽

Kobe C. Yuen ◽

Silke Gillessen ◽

Edward E. Kadel ◽

Dana Rathkopf ◽

...

Keyword(s):

Prostate Cancer ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant

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Faculty Opinions recommendation of Phase 3, randomized, placebo-controlled study of zibotentan (ZD4054) in patients with castration-resistant prostate cancer metastatic to bone.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717955961.793460904 ◽

2012 ◽

Author(s):

Bruno Andreoni ◽

Gianmarco Contino

Keyword(s):

Prostate Cancer ◽

Controlled Study ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant

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Reply to Johann S. de Bono, Maha Hussain, and Jinyu Kang’s Letter to the Editor re: Konrad H. Stopsack. Efficacy of PARP Inhibition in Metastatic Castration-resistant Prostate Cancer is Very Different with Non-BRCA DNA Repair Alterations: Reconstructing Prespecified Endpoints for Cohort B from the Phase 3 PROfound Trial of Olaparib. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.09.024

European Urology ◽

10.1016/j.eururo.2020.12.018 ◽

2020 ◽

Author(s):

Konrad H. Stopsack

Keyword(s):

Prostate Cancer ◽

Parp Inhibition ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Letter To The Editor

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Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial

10.1016/s0140-6736(21)00580-8 ◽

2021 ◽

Vol 398 (10295) ◽

pp. 131-142

Author(s):

Christopher Sweeney ◽

Sergio Bracarda ◽

Cora N Sternberg ◽

Kim N Chi ◽

David Olmos ◽

...

Keyword(s):

Prostate Cancer ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Double Blind ◽

Castration Resistant

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Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer: Extended Analysis of the Phase 3 PREVAIL Study

European Urology ◽

10.1016/j.eururo.2016.07.032 ◽

2017 ◽

Vol 71 (2) ◽

pp. 151-154 ◽

Author(s):

Tomasz M. Beer ◽

Andrew J. Armstrong ◽

Dana Rathkopf ◽

Yohann Loriot ◽

Cora N. Sternberg ◽

...

Keyword(s):

Prostate Cancer ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Extended Analysis

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A phase 3, randomized, double-blind trial of nivolumab or placebo combined with docetaxel for metastatic castration-resistant prostate cancer (CheckMate 7DX)

10.26226/morressier.613756f1842293c031b5830d ◽

2021 ◽

Author(s):

Karim Fizazi

Keyword(s):

Prostate Cancer ◽

Double Blind Trial ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Double Blind ◽

Blind Trial ◽

Castration Resistant

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Cabozantinib Versus Mitoxantrone-prednisone in Symptomatic Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 3 Trial with a Primary Pain Endpoint

European Urology ◽

10.1016/j.eururo.2018.11.033 ◽

2019 ◽

Vol 75 (6) ◽

pp. 929-937 ◽

Author(s):

Ethan M. Basch ◽

Mark Scholz ◽

Johann S. de Bono ◽

Nicholas Vogelzang ◽

Paul de Souza ◽

...

Keyword(s):

Prostate Cancer ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant

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713 ABIRATERONE ACETATE IN METASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS WITHOUT PRIOR CHEMOTHERAPY - INTERIM ANALYSIS OF THE COU-AA-302 PHASE 3 TRIAL

The Journal of Urology ◽

10.1016/j.juro.2013.02.272 ◽

2013 ◽

Vol 189 (4S) ◽

Author(s):

Fred Saad ◽

Neal D Shore ◽

Hendrik Van Poppel ◽

Dana Rathkopf ◽

Matthew R. Smith ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Patients ◽

Interim Analysis ◽

Abiraterone Acetate ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Prior Chemotherapy ◽

Castration Resistant

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Patient-reported outcomes following enzalutamide or placebo in men with non-metastatic, castration-resistant prostate cancer (PROSPER): a multicentre, randomised, double-blind, phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(18)30898-2 ◽

2019 ◽

Vol 20 (4) ◽

pp. 556-569 ◽

Author(s):

Bertrand Tombal ◽

Fred Saad ◽

David Penson ◽

Maha Hussain ◽

Cora N Sternberg ◽

...

Keyword(s):

Prostate Cancer ◽

Patient Reported Outcomes ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Double Blind ◽

Castration Resistant ◽

Patient Reported

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Era 223—A Phase 3 Trial of Radium-223 Dichloride (Ra-223) in Combination with Abiraterone Acetate (Aa) and Prednisone in the Treatment of Asymptomatic or Mildly Symptomatic Chemotherapy-Naïve Patients with Bone-Predominant Metastatic Castration-Resistant Prostate Cancer (Crpc)

Annals of Oncology ◽

10.1093/annonc/mdu336.50 ◽

2014 ◽

Vol 25 ◽

pp. iv278 ◽

Author(s):

M.R. Smith ◽

C. Parker ◽

B. Tombal ◽

K. Miller ◽

F. Saad ◽

...

Keyword(s):

Prostate Cancer ◽

Abiraterone Acetate ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Download Full-text

Efficacy of PARP Inhibition in Metastatic Castration-resistant Prostate Cancer is Very Different with Non-BRCA DNA Repair Alterations: Reconstructing Prespecified Endpoints for Cohort B from the Phase 3 PROfound Trial of Olaparib

European Urology ◽

10.1016/j.eururo.2020.09.024 ◽

2020 ◽

Author(s):

Konrad H. Stopsack

Keyword(s):

Prostate Cancer ◽

Parp Inhibition ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant

Download Full-text