Simulations of human lysozyme: Conformations triggering amyloidosis in 156T mutant

Author(s):  
G. Moraitakis ◽  
J. M. Goodfellow
Keyword(s):  
1978 ◽  
Vol 24 (12) ◽  
pp. 2155-2157 ◽  
Author(s):  
T L Peeters ◽  
Y R Depraetere ◽  
G R Vantrappen

Abstract We present a radioimmunoassay for lysozyme in human serum, based upon human lysozyme isolated from the urine of leukemic patients and antiserum prepared against this lysozyme in the goat. In the separation step, a second antibody is used. By properly adjusting the concentrations of unlabeled and 125I-labeled lysozyme and of the antibodies, maximal precision (SD, 0.04 mg/litre) was obtained in the range 0.00 to 2.00 mg/litre. In 20 normal volunteers the lysozyme concentration was 4.6 +/- 0.8 mg/litre (mean +/- SD), in 13 patients with monocytic leukemia 34.4 +/- 8.6 mg/litre. Correlation with lysoplate determinations was excellent in leukemic sera (r = 0.97) but was poor in normal sera (r = 0.35), possibly owing to the existence of isoenzymes.


2021 ◽  
Vol 105 (3) ◽  
pp. 1041-1050
Author(s):  
Luqiang Jia ◽  
Teng Li ◽  
Yixuan Wu ◽  
Chunsen Wu ◽  
Huaxiang Li ◽  
...  

1991 ◽  
Vol 266 (10) ◽  
pp. 6456-6461 ◽  
Author(s):  
Y Taniyama ◽  
R Kuroki ◽  
F Omura ◽  
C Seko ◽  
M Kikuchi

1988 ◽  
Vol 152 (3) ◽  
pp. 962-967 ◽  
Author(s):  
Yoshio Taniyama ◽  
Yoshio Yamamoto ◽  
Masafumi Nakao ◽  
Masakazu Kikuchi ◽  
Morio Ikehara

2000 ◽  
Vol 28 (5) ◽  
pp. A410-A410
Author(s):  
J. Funahashi ◽  
K. Takano ◽  
Y. Yamagata ◽  
M. Nakasako ◽  
K. Yutani

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0118626 ◽  
Author(s):  
Dainan Cao ◽  
Hanyu Wu ◽  
Qingyuan Li ◽  
Yingmin Sun ◽  
Tongxin Liu ◽  
...  

2001 ◽  
Vol 43 (4) ◽  
pp. 413-419 ◽  
Author(s):  
Koji Inaka ◽  
Eiko Kanaya ◽  
Masakazu Kikuchi ◽  
Kunio Miki

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